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Mechanical Engineer, Scientific Instrumentation

Arcadia Science


Job Location:

Emeryville, CA - USA

Monthly Salary: $ 150000 - 185000
Posted: 4 June 2026 (30+ days ago)
Application Deadline: 1 September 2026
Vacancies: 1 Vacancy
The job posting is outdated and position may be filled

Job Summary

A Bit About Us

We are Arcadia Science an evolutionary biology company founded and led by scientists. Our mission is to turn natural innovations into real-world solutions by developing systematic and quantitative approaches to leveraging biology for therapeutics R&D. We share our research as openly as possible to accelerate discovery and make our work broadly useful.

About the role

The Mechanical Engineer will be part of the Foundry Arcadias division at the interface between R&D and commercial deployment. The goal of this division is to take scientifically validated tools and capabilities from the research team and productionize them for broader use. The Foundrys first focus is Raman spectroscopy. This role will report directly to the CEO.

You will start with an effort to transform AutoOpenRaman an open-source automated Raman spectrometer we developed for biological research into a compact safe manufacturable benchtop instrument. That means designing a Class 1 laser enclosure defining the mechanical architecture of the integrated system and creating a build process reproducible enough to scale. You will work closely with optical and software engineers and the scientists who will use the instrument every day. From there you will help define what external deployment looks like contributing to a product that can be quickly and affordably placed in partner labs and companies.

What youll work on
  • Define the mechanical envelope of the InstantRaman enclosure working within the constraints of the optical path motorized stage and Class 1 laser safety requirements
  • Design and prototype an enclosure that achieves Class 1 laser safety certification and is manufacturable at small-scale production runs (1050 units)
  • Own the mechanical bill of materials tolerancing and assembly documentation for reproducible builds
  • Consolidate the current electronics (stage controller shutter calibration light source laser) into a single integrated mechanical system with clean cable routing and accessible service points
  • Work with the optical instrument engineer to co-develop a compact optical path that fits within the enclosure envelope enclosure design drives the layout not the other way around
  • Engage fabrication vendors sheet metal shops and laser safety review as needed
  • Develop design-for-manufacturability (DFM) documentation ahead of any transition from prototype to production
What were looking for

Youll be well-suited for this role if you have:

  • BS or MS in mechanical engineering or a closely related field with hands-on experience designing and building scientific or analytical instruments
  • Experience designing enclosures or housings for regulated or safety-critical hardware (laser systems high-voltage electronics or similar)
  • Proficiency in CAD (SolidWorks Fusion 360 or equivalent) including tolerancing assembly modeling and drawing packages for fabrication
  • Experience with sheet metal design vendor sourcing and iterating through fabrication cycles
  • Ability to collaborate tightly with optical and software engineers you understand that your mechanical design decisions affect optical alignment stability thermal behavior and software-controlled motion
  • Familiarity with electromechanical integration: specifying and installing stepper motor stages limit switches interlocks or similar embedded systems
  • Ability to communicate with biologists and understand what actually matters for a life science instrument: ergonomics sample loading serviceability and ease of use are part of the design problem
Nice to have
  • Direct experience with laser systems or enclosed laser instrumentation including Class 1 or Class 3B/R safety design
  • Familiarity with optical bench layouts cage systems or Raman/spectroscopy instruments
  • Experience with design for manufacturability and transitioning from prototype to small-scale production
  • Experience with relevant experimental workflows and the physical realities of laboratory environments (vibration humidity bench space constraints
$150000 - $180000 a year
Successful applicants can expect to be compensated between $150000$185000 with benefits and a competitive equity offering depending on experience level. The position will require the individual to be on-site at our Emeryville California headquarters.

Please submit a resume and fully answer all application questions addressing your interest in and qualifications for the position. The review process will involve in-person interviews and a short practical work test. Employment offers are contingent on reference and background checks.

Arcadia is an equal opportunity workplace; we welcome people from all backgrounds and communities. We provide competitive compensation and practical benefits to keep you happy and healthy so that you can do your best work.

Required Experience:

IC


About Company

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Arcadia Science is pushing the boundaries of open science and innovating at every step in the research, development, and commercialization process.

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