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Manager, Product Lifecycle Management Operations

Illumina


Job Location:

San Diego, CA - USA

Monthly Salary: $ 107700 - 161500
Posted: 3 June 2026 (30+ days ago)
Application Deadline: 8 October 2026
Vacancies: 1 Vacancy
The job posting is outdated and position may be filled

Job Summary

What if the work you did every day could impact the lives of people you know Or all of humanity

At Illumina we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person in every role has the opportunity to make a difference. Surrounded by extraordinary people inspiring leaders and world changing projects you will do more and become more than you ever thought possible.

TheManagerPLM Operationsis a high-impactrolethat balancesstrategic leadership operational execution and peopledevelopment. This positiondevelops key partnershipsacrossEngineering Quality Regulatory Supply Chainand Commercial departments toenable excellence throughout the product lifecycle.Success in this role looks like amotivated team with clear ownership and predictable delivery resulting in high PLM-stakeholder satisfaction.The ideal candidatehasstrong negotiating and influencing skillsthe ability tohandle multiple tasks in parallel and communicate effectivelyacrossall levels of the organization.

Responsibilities:

  • Lead team of Change Analystssupporting New Product Introduction and Sustaining Operations at multiple sites.Align business demand with team capacity.

  • Setclear performance expectationsandchampion employeedevelopment.

  • Acts as subject matter expert (SME) of PLM process requirements; define and apply best practices.

  • Lead global alignment discussionson strategyandrequirements.

  • Trend analyze and report onchange managementdatain order toimprove product and process; develop recommendations based on data analysis.

  • Lead initiatives to reduce aging changes improve throughput and eliminate recurring process pain points.

Requirements:

  • Bachelors Degree in an engineering or scientific discipline

  • Typically requires8years ofrelevantexperience inengineering orsimilar withhandson understanding of PLM systems (e.g. Teamcenter or similar) and product lifecycle processes.

  • Strongly preferred:1-3 years of managementexperience

  • Consistent track record of collaboration including the ability to work with cross-functional teams across complex ecosystemswith an enterprise mindset

  • Proven peoplemanagement skills including coaching performance management and conflict resolution.

  • Ability to navigate and influence across all levels of an organization translating strategic vision into tangible outcomes

  • Experience applying quality regulation standards (e.g. 21CFR820 ISO 13485 ISO 14971 IVDD)

  • Strong understanding of manufacturing methods & terminology.

  • Knowledge of Lean Tools and Root Cause Analysis methodologies.

  • Proficient in process mapping with demonstrated track-record ofdriving solutions through continuousimprovementcultureand project management.

  • Occasional travelnight and/or weekend work may be requiredto support 24-hour global manufacturing operation.

The estimated base salary range for the Manager Product Lifecycle Management Operations role based in the United States of America is: $107700 - $161500. Should the level or location of the role change during the hiring process the applicable base pay range may be updated accordingly. The range reflects longterm growth in the role; therefore most candidates are hired between the minimum and middle of the range. Placement depends on experience skills location and internal equity. Additionally all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work including access to genomics sequencing family planning health/dental/vision retirement benefits and paid time off.

We are a company deeply rooted in belonging promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation Illumina has always prioritized openness collaboration and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay regardless of gender ethnicity or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences increase cultural awareness and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex race creed color gender religion marital status domestic partner status age national origin or ancestry physical or mental disability medical condition sexual orientation pregnancy military or veteran status citizenship status and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local state and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local state and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process please contact To learn more visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Required Experience:

Manager