Lead Scientist, Analytics
New York City, NY - USA
Job Summary
About the Company
Helaina is a cutting-edge nutrition biotech company creating nutrients of the future. Helaina leverages a world-class team to develop breakthrough ingredients designed to improve health for everyone.
The companys vision is to build a nutrient platform that powers the future of consumer health through bioactive proteins. Our journey was inspired by breast milk a unique substance that is both food and medicine. Helainas Founder Laura Katz saw consumers seeking out these proteins for their proven ability to boost immunity gut health and brain development. Helaina was founded on the belief that we could replicate this profound function to create ingredients with real impact.
Helainas first ingredient effera is a holy grail molecule that is an identical replica of human lactoferrin one of breast milks most powerful proteins. As a dynamic bioactive protein effera can adapt to the bodys specific needs offering multiple benefits:
supports iron absorption and womens health
boosts immunity by fighting infections
crosses the blood-brain barrier for cognitive benefits
reduces inflammation for sports recovery and longevity
About the Role
In this role youll contribute directly to Helainas milestones by designing performing and troubleshooting experiments toward the Analytics teams objectives and leading that teams day-to-day delivery. This is an excellent opportunity for someone hungry to work in a startup environment and ready to make a big impact on the future of nutrition. This is a full-time on-site lab-based role at Helainas NYC office.
What youll do:
Lead the development and validation of analytical methods for characterization of recombinant proteins and food ingredients including sample preparation and physicochemical analysis of lactoferrin and other proteins by techniques such as HPLC LC-MS and SDS-PAGE
Provide analytical support to R&D on strain engineering and process development for expression and production of recombinant proteins
Provide analytical support for product characterization across food applications to support client requests from our commercial team
Own daily operation and maintenance of major equipment including (U)HPLC and mass-spectrometry systems
Perform method development transfer validation and operations including release and stability studies for food ingredients and finished products
Work with external resources including CROs and CMOs/CDMOs to advance company objectives and milestones
Provide technical support for regulatory filings health-authority questions change control and quality impact assessments
Analyze interpret and present data to internal and external audiences
Own project planning and execution at the team level escalating risks proactively enforcing quality and process standards and developing the analytics team
About you:
You have a PhD MS or BS in analytical chemistry analytical biochemistry biochemistry biology chemistry or a related scientific discipline with 10 years of in-lab experience in a biotech or academic setting
You have deep knowledge of analytical techniques for protein purification and analysis such as chromatography (RP IEX SEC and HILIC)
You have deep expertise in mass-spectrometry characterization of proteins including intact protein measurement peptide mapping and glycosylation and other post-translational-modification analysis
You have experience developing and validating proteomics and metabolomics workflows
You have deep expertise analyzing and communicating complex mass-spectrometry data (experience with Skyline Spectronaut MaxQuant and UniDec is preferred)
You have a strong working knowledge of analytical method development validation transfer and root-cause analysis
You are an effective communicator within a collaborative scientific team and in translating science for non-technical audiences
You are eager to make an impact in a team environment and you are energetic creative and personally motivated by the future of food and/or biological products
Spectroscopy (UV fluorescence CD) and SDS-PAGE/western blotting are a plus
Bonus points for prior applied experience with recombinant-protein purification and analysis and for publications in peer-reviewed journals patents SOPs and/or regulatory filings
Benefits
Helaina was founded on the belief that families should have freedom of choice. We are committed to providing an inclusive workplace that supports our teams health and wellbeing. A few highlights:
Medical vision and dental coverage
Short and long-term disability insurance
401k match (up to 3%)
Unlimited vacation days including an all-company holiday between Christmas and New Year
Paid Parental Leave for both parents flexible return-to-work program
Commuter Benefits
Learn more about Helaina: is an Equal Opportunity Employer. Dont meet every single requirement Studies have shown that women and people of color are less likely to apply to jobs unless they meet every single qualification. At Helaina we are dedicated to building a diverse inclusive and authentic workplace if youre excited about this role but your past experience doesnt align perfectly with every qualification listed we encourage you to apply anyway. You may be the strongest candidate for this or other roles. For more information contact .
All candidates must be available to work on-site at Helainas office in NYC.
Compensation is market-competitive with a yearly cash base of $110k $160k plus equity.
We use a disciplined approach to compensation we believe this is the only way to create a consistent strategic and equitable structure that unlocks healthy growth for our organization. We decide any hires offer based on three factors: (1) expected performance in the role based on performance in the interview process and proximity of experience; (2) seniority meaning amount of relevant experience; and (3) location reflecting different costs of living.
Required Experience:
Senior IC