Faculty Appointment in Radiology and Biomedical Imaging

Responsibilities may include the development characterization and validation of novel imaging biomarkers with PET pharmacokinetic modeling of novel radiopharmaceuticals development of advanced image reconstruction algorithms for quantitative PET and PET/MR imaging and the development of deep learning methods to improve quantitative PET imaging.

Yale School of Medicine educates and nurtures creative leaders in medicine and science promoting curiosity and critical inquiry. We advance discovery and innovation fostered by partnerships across the university our local community and the world. We care for patients with compassion and commit to improving the health of all people.

The Yale University PET Center located on Howard Avenue in New Haven CT is a 22000 sq. ft. facility established to advance the interests of Yale clinicians scientists and students in molecular imaging research. The Yale University PET Center is comprised of a technologically advanced radiochemistry laboratory engaged in the development and use of a rich set of PET radiopharmaceuticals labeled with the most common PET isotopes (11C 15O 13N and 18F); and an imaging and data analysis section that oversees scanning procedures and optimizes data acquisition and analysis.

The Yale University PET Center collaborates with other School of Medicine departments to provide educational opportunities for doctoral and postdoctoral trainees. Collaborations with industry partners serve to advance the use of molecular imaging in new medication discovery and the development of new PET radiopharmaceuticals. Current research interests focus on disorders of the central nervous system (CNS) oncology cardiology and diabetes.

Successful candidates should have a Ph.D. or MD/PhD in biomedical engineering physics electrical and computer engineering computer science applied mathematics or related fields. They should have experience and a track record of publications in two of the following areas:

• PET imaging physics modeling of PET data and corresponding physical corrections.
• Tomographic image reconstruction including conventional reconstruction algorithms and penalized image reconstruction techniques.
• Radiotracer development acquisition of experimental data including arterial blood and plasma as well as radiometabolite analysis using HPLC techniques pharmacokinetic modeling including blood-based and reference region-based models and use of numerical solvers for model fitting.
• Deep learning tools and methods for image denoising reconstruction segmentation and classification.

Besides a strong background in the listed areas candidates should demonstrate the following technical skills:

• Experience with computer science and data science image processing and analysis.
• Proficiency with programming languages such as C/C Python MATLAB R Linux scripting (e.g. bash).
• Strong verbal and written communication skills demonstrated by publication track record and experience with grant writing.
• Mentoring skills for undergraduate and graduate students interns and visitors.

Besides the requirements listed above additional desired qualifications include:

• Experience with MR imaging and MR image reconstruction and analysis.
• Experience with brain imaging and knowledge of biomarkers in Alzheimers and other neurodegenerative diseases.
• Familiarity with optimization theory and applications to inverse problems.