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Executive Director, Global Total Rewards & HR Operations


Job Location:

Waltham, MA - USA

Monthly Salary: Not provided by the employer
Posted: 28 May 2026 (30+ days ago)
Application Deadline: 25 August 2026
Vacancies: 1 Vacancy
The job posting is outdated and position may be filled

Job Summary

Role Summary

The Executive Director Global Total Rewards & HR Operations serves as the enterprise leader responsible for defining and advancing Decipheras global Total Rewards strategy HR systems and HR operations model. This role will architect and operationalize a fully integrated scalable infrastructure spanning compensation benefits HR technology and service delivery to support business growth and ONO integration.

The Executive Director is accountable for both the strategy and execution of compensation programs globally serving as the primary leader overseeing compensation philosophy design decision-making and delivery. This role partners closely with the CHRO and key stakeholders to ensure that rewards programs systems and operations are competitive data-driven and aligned to business priorities.

This role also leads and develops a team ensuring the organization has the capabilities structure and expertise to deliver on its strategic objectives while driving strong governance operational excellence and a consistent employee experience across geographies.

Key Responsibilities
Total Rewards Strategy 40%

Defines and leads a comprehensive globally aligned Total Rewards strategy that drives attraction retention performance differentiation and enterprise value creation.

  • Define and lead a comprehensive global Total Rewards strategy with direct accountability for end-to-end compensation strategy and execution (base pay benefits incentives and equity)
  • Oversee executive commercial and broad-based compensation design including incentive plans and pay-for-performance structures
  • Establish compensation philosophy governance frameworks and decision-making principles to support consistent and equitable outcomes
  • Lead job architecture leveling frameworks and global market pricing
  • Direct annual compensation cycles (merit bonus equity) ensuring alignment with business strategy and financial plans
  • Set the strategy and governance for global benefits programs (health retirement wellness) ensuring competitiveness compliance and cost effectiveness in partnership with subject matter experts
  • Serve as a trusted strategic advisor to the CHRO and key stakeholders providing guidance on workforce cost compensation strategy rewards investments and people-related risk
  • Ensure global alignment and integration of Total Rewards programs with ONO while maintaining relevance to Decipheras business and culture

HR Systems Data & Analytics 25%

Establishes a scalable HR technology and data ecosystem that enables insight-driven decision-making operational efficiency and global integration.

  • Own the strategy roadmap and governance for Workday and the broader HR technology ecosystem
  • Drive system optimization integration and automation to improve employee and manager experience
  • Establish HR data governance controls and reporting frameworks to ensure accuracy and compliance
  • Advance people analytics capabilities to enable data-driven decision-making across compensation workforce planning and talent strategy
  • Partner with IT Finance and external vendors to ensure scalability integration and long-term system effectiveness
  • Ensure alignment of HR systems and data structures with ONO to support global reporting and integration

HR Operations & Service Delivery 20%

Designs and governs a scalable globally aligned HR operations model that ensures consistent compliant and high-quality employee and manager experience.

  • Define and evolve a scalable global HR operations model setting the strategy governance and priorities that enable operational excellence through process standardization automation and continuous improvement across compensation benefits and core HR processes
  • Ensure consistent compliant and efficient execution of HR programs and processes through clear governance controls and service delivery frameworks with a focus on accuracy risk mitigation and service quality
  • Establish and maintain policies SOPs and governance structures to support audit readiness regulatory compliance and operational consistency across regions
  • Partner across HR and the business to deliver a seamless and consistent employee and manager experience with clear ownership accountability and service model clarity
  • Oversee operational performance through defined metrics and KPIs enabling datadriven decisions to improve efficiency effectiveness and user experience
  • Align HR operations processes and service delivery with ONO frameworks where appropriate while preserving flexibility to meet Decipheras business needs

Leadership & Team Development 10%

Builds and leads a high-performing Center of Excellence strengthening organizational capability accountability and long-term scalability.

  • Lead coach and develop a high-performing team across Total Rewards HRIS and HR Operations
  • Build organizational capability including team structure skills and operating model to support a scalable Center of Excellence
  • Foster a culture of accountability collaboration and continuous improvement

Other duties and responsibilities as assigned 5%


Qualifications :

Required Qualifications

  • Demonstrated experience in Total Rewards Compensation HR Systems with a strong track record of designing and scaling global Total Rewards strategies executive compensation frameworks and HR operations in a complex multiregion environment including experience operating in or partnering across global organizations
  • 15 years of progressive HR experience including deep expertise in Total Rewards HR systems (e.g. Workday) and HR operations
  • 8 years of leadership experience including leading global or enterprise teams
  • Demonstrated experience designing and leading compensation strategies including executive compensation and incentive plan design
  • Strong expertise in HRIS strategy data governance and HR analytics
  • Experience operating in global matrixed organizations with complex stakeholder environments
  • Strong understanding of compensation benefits and HR compliance across the U.S. and EU
  • Proven ability to influence senior executives and translate business strategy into people programs
  • Demonstrated ability to develop strategy and translate it into execution including building roadmaps driving implementation and delivering measurable outcomes
  • Strong business and financial acumen with the ability to evaluate workforce costs model compensation investments and align rewards strategies with financial and business objectives
  • Strong analytical and data-driven decision-making capabilities

Preferred Capabilities

  • Advanced degree (MBA MHRM or related discipline)
  • Experience operating in and supporting integration in a global environment and collaborating with headquarters and/or a Japanese parent organization
  • Experience building or transforming a Total Rewards and/or HR operations COE from scaling or evolving environments
  • Professional certifications (e.g. CCP CEBS)
  • Strong analytical and data-driven decision-making capabilities
  • Demonstrated success driving HR transformation technology implementations and change management
  • Ability to balance strategic leadership with operational execution in a fast-paced environment

Additional Information :

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $246000 - $338000. Actual compensation packages will depend on various factors including but not limited to depth of experience education skillset overall performance and/or location.

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Decipheras competitive total rewards strategy that also includes annual performance bonus a long-term incentive plan full range of benefits and other incentive compensation plans (if applicable)

Benefits:

  • Competitive salary and annual bonus.
  • Comprehensive benefits package including medical dental vision insurance 401(k) retirement plan with company match and more.
  • Generous parental leave and family planning benefits.
  • Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.


Remote Work :

No


Employment Type :

Full-time