Director, Clinical Imaging, Translational Sciences-Immunology

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

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Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Translational Discovery & Development Biomarkers

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House Pennsylvania United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at Immunology

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Director Clinical Imaging-Translational Science- Immunology to be in Spring House PA or Cambridge MA.

The Director Clinical Imaging will provide strategic and scientific leadership for the development validation and delivery of imaging-derived endpoints to enable high-impact decision-making across the Immunology portfolio with a primary focus on Gastrointestinal (GI) diseases. The role is US-based (Spring House PA or Cambridge) and sits within the Translational Science organization operating in a highly matrixed environment across Immunology Disease Area Strategy Clinical Development Data Sciences Regulatory and operational functions. This position is intentionally scoped and graded to ensure imaging and digital capabilities are positioned as strategic assets for Immunology driving endpoint innovation for precision medicine from early to late phase. The Director will balance innovation platform building and technical delivery ensuring that advanced measurement approaches are translated into fit-for-purpose scalable solutions that support portfolio objectives.

Key Responsibilities:

Scientific & Strategic Technology Leadership

• Lead the GI-focused imaging measurement strategy across Immunology assets spanning early through late-phase clinical development.
• Shape endpoint strategies integrating imaging measurements to support mechanistic understanding proof-of-concept and decision-enabling outcomes including regulatory.
• Partner with Disease Area Strategy and Translational Science leaders to ensure alignment with portfolio priorities and clinical development plans.
• Contribute to investment cases governance discussions and portfolio reviews articulating value readiness and risk.

Clinical Trial Delivery & Execution

• Provide scientific oversight and accountability for imaging endpoints across early- and late-phase clinical trials.
• Ensure methods have an operationally delivery model to scale.
• Partner with clinical and operational partners across the organization Data Sciences and external vendors/CROs to ensure on-time high-quality delivery.
• Support regulatory interactions related to imaging endpoints.

Innovation AI & Capability Building

• Identify and advance next-generation imaging technologies with clear trajectories to GI pipeline impact from novel molecular methods through to AI-based structural endpoints.
• Lead the integration of AI-enabled analytics for imaging and digital endpoints in close partnership with the Data Science organization.
• Co-develop AI-based solutions (e.g. automated image analysis quantitative feature extraction digital signal interpretation) to improve scalability reproducibility and decision-making in high impact areas.
• Build and sustain external collaborations with academia technology partners and pre-competitive consortia.
• Translate emerging methods into pragmatic clinical solutions balancing innovation with feasibility and timelines.

Matrix Leadership & Influence

• Partner closely with the Imaging and Digital Health team colleagues to drive innovation and delivery across disease areas.
• Operate effectively in a complex global matrix environment and influence to guide strategy.
• Serve as a trusted scientific advisor to project teams DAS leadership and senior stakeholders.
• Communicate complex technical concepts with clarity and impact to diverse audiences.
• Mentor and develop scientists and matrix partners contributing to a culture of scientific excellence and accountability.

Qualifications & Experience

Required

• PhD or MD or equivalent advanced degree in a relevant scientific or clinical discipline.
• Minimum 10 years of experience in pharmaceutical or biotech R&D.
• Demonstrated experience applying imaging in interventional clinical trials.
• Proven ability to balance innovation with reliable execution in complex development environments.
• Exceptional written verbal and presentation skills.
• Strong track record of working effectively in highly matrixed global organisations.

Preferred

• Experience in Gastrointestinal diseases including Crohns disease and ulcerative colitis.
• Experience working in close partnership with AI/ML teams to develop or deploy analytics for clinical trials.
• Familiarity with AI-enabled image analysis digital biomarker pipelines or quantitative imaging workflows.
• Exposure to regulatory interactions involving imaging endpoints.
• Experience managing external partnerships with technology vendors CROs and academic collaborators.

Success in the First 12 Months

• Establish clear ownership and strategic direction for GI imaging endpoints aligned to GI Disease Area Strategy and clinical development teams.
• Establish an effective operating model with the Data Science organisation to deliver AI-enabled analytics for imaging and digital endpoints.
• Exhibit disciplined scientific and portfolio decision-making including refinement or discontinuation of approaches where pipeline value is not compelling.
• Be recognised by project teams and senior stakeholders as a trusted scientific and strategic leader who balances innovation with delivery.

Why Johnson & Johnson

At Johnson & Johnson Innovative Medicine we are redefining how clinical evidence is generated. This role offers the opportunity to shape how imaging digital measurement and AI-enabled analytics transform Immunology drug development delivering tangible impact for patients while building future-facing scientific capabilities.

The anticipated base pay range for this position is $160000 to $276000

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance.

Employees may be eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Companys long-term incentive program.

Employees are eligible for the following time off benefits:

Vacation up to 120 hours per calendar year

Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington up to 56 hours per calendar year

Holiday pay including Floating Holidays up to 13 days per calendar year

Work Personal and Family Time - up to 40 hours per calendar year

Additional information can be found through the link below. For additional general information on company benefits please go to: - & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via . Internal employees contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Required Skills:

Preferred Skills:

Clinical Evaluations Coaching Critical Thinking Drug Discovery Development Entrepreneurship Good Clinical Practice (GCP) Leadership Medicines and Device Development and Regulation Organizing Regulatory Affairs Management Relationship Building Research Documents Safety-Oriented Scientific Research Standard Scientific Processes and Procedures Strategic Change Study Management

The anticipated base pay range for this position is :

$164000.00 - $282900.00

Additional Description for Pay Transparency: