Director, Analytical Biochemistry & In vitro Assays

Position Overview:

The incumbent will lead a team and provide high level expertise and leadership capacity in Analytical Biochemistry and In vitro assays in support of drug discovery efforts using novel modalities within and external to CSL R&D. This role sits at the interface of discovery research translational sciences DMPK toxicology clinical pharmacology CMC and regulatory functions. It requires scientific expertise with multiple modalities across Research and Development proven experience working with and managing external academic and industry partners and leadership skills to drive innovation and ensure the successful discovery and progression of drug candidates.

Work Environment:

*** This is a hybrid position based in Waltham MA with a minimum of 3 days onsite required on a weekly basis. Relocation and mobility assistance are not provided.

Key Responsibilities:

• Leadership and development of a team of Sr/Scientists fostering innovation and excellence development and execution of bioanalytical strategies that support discovery preclinical and early clinical development programs

• Support the selection of appropriate therapeutic modalities most importantly DNA and RNA-based therapies potentially peptides and vaccines for specific disease targets

• Lead and participate in external due diligence and provide expert advice on modality suitability and risks

• Contribute to the Drug Discovery Leadership Team driving CSLs drug discovery efforts

• Foster a collaborative and high-performance culture within the team encouraging innovation and continuous learning

Leadership and Management:

• Provide strategic direction for research projects ensuring alignment with overall company goals and objectives

• Define the bioanalytical strategy across a portfolio of programs build assays that generate critical efficacy target engagement biomarker and immunogenicity data

• Facilitate effective communication and collaboration among team members and across departments

• Manage team resources including budget personnel and equipment to optimize productivity and efficiency

• Lead and manage internal research activities and manage external projects including performing wet lab due diligence activities ensuring necessary resources and expertise

• Lead and manage research and lifecycle management activities for RNA-based vaccines

Scientific Excellence:

• Oversee the development optimization and validation of novel analytical methods and in vitro assays

• Ensure data generation is robust reproducible and meets regulatory standards and guidelines

• Foster collaboration with cross-functional teams to integrate assay data into broader research programs contribute to the advancement of therapeutic candidates from discovery through to clinical development

Innovation and Development

• Identify and evaluate emerging technologies methodologies and best practices to enhance analytical capabilities and assay performance

• Drive continuous improvement initiatives implementing new techniques and technologies to keep the team at the forefront of the field

• Contribute to the scientific community through publications in peer-reviewed journals presentations at conferences and participation in professional organizations

Project Management:

• Plan execute and monitor research projects ensuring efficient use of resources and timely delivery of project milestones and deliverables

• Develop detailed project plans including objectives timelines and risk management strategies

• Communicate project progress challenges and outcomes to stakeholders senior management and external partners

• Ensure compliance with all relevant regulations guidelines and quality standards throughout the project lifecycle

Minimum Qualifications:

• Postgraduate degree (preferably PhD). in Molecular Biology Biochemistry and/or extensive experience in relevant industry or academic environment scientific and people leadership

• 10 years of experience in analytical biochemistry and in vitro assay development with a proven track record of successful research and development projects

• Prior experience in a leadership role is essential

• Experience with novel modalities such as gene therapy peptides cell therapy or RNA-based therapeutics and vaccines

• Strong expertise in analytical method development validation and regulatory requirements

• Proven track record of scientific innovation and contribution to the field

• Demonstrated effective leadership communication and project management skills

• Familiarity with advanced analytical techniques and instrumentation (mass spec)

• Demonstrated ability to work effectively in a cross-functional and dynamic environment

The expected base salary range for this position at hiring is $228000 - $294000. Please note this salary range reflects the minimum and maximum base pay that CSL expects to pay for this position at the Waltham MA USA work location at the time of this posting. Individual base salary for a successful candidate is determined by qualifications skill level experience competencies and other relevant addition to base salary total compensation for this role may also include incentive compensation and equity.

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CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients needs by using the latest technologies we discover develop and deliver innovative therapies for people living with conditions in the immunology hematology cardiovascular and metabolic respiratory and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation recombinant protein technology and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.

CSL Behring operates one of the worlds largest plasma collection networks CSL Plasma. Our parent company CSL headquartered in Melbourne Australia employs 32000 people and delivers its lifesaving therapies to people in more than 100 countries.

To learn more about CSL CSL Behring CSL Seqirus and CSL Vifor visit and CSL Plasma at Benefits

For more information on CSL benefits visit How CSL Supports Your Well-being CSL.

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Director