Director AI Digital Biology

The Director - Artificial Intelligence (AI) leads the engineering and research team that builds and delivers Mayo Clinic DigPaths digital-biology technology platforms accountable for translating the organizations vision into validated deployed products. Working closely with the Vice President Digital Biology the Chief Medical Officer and the Chief Science Officer the Director helps shape technical direction and owns its executionthe roadmap delivery and technical quality for DigPaths core model and platform portfolio including foundation and task-specific models AI Virtual Cells biological digital twins and digital biomarker discovery. Directing a multidisciplinary team of AI/ML engineers software developers and research scientists the Director turns clinical and scientific priorities into engineering execution - partnering with the CMO for clinical relevance and the CSO for scientific rigor - to consistently ship breakthrough tools with speed technical excellence and unwavering focus on Mayo Clinics core value: the needs of the patient come first.

The Director partners closely with executive leaders clinical and business stakeholders and technical teams to ensure AI initiatives are aligned with enterprise strategy governance expectations and operational readiness. The role leads multidisciplinary teams across product operations and technology and serves as a key connector between strategy and execution.

Key Responsibilities

• AI Strategy & Program Leadership: Lead development and execution of enterprise AI strategy and multi-year roadmaps aligned with organizational goals.
• Portfolio Oversight: Oversee intake prioritization and sequencing of AI initiatives; balance value feasibility risk and capacity across portfolios.
• CrossFunctional Leadership: Partner with clinical operational technical legal compliance and data leaders to advance AI initiatives from concept through deployment.
• Governance & Responsible AI: Ensure AI initiatives adhere to governance frameworks ethical standards regulatory requirements and risk management practices.
• Operational Enablement: Establish operating rhythms performance metrics and reporting mechanisms to track progress outcomes and value realization.
• Stakeholder Engagement: Serve as a trusted advisor to senior leaders; communicate AI strategy progress and impact through executivelevel updates and presentations.
• People & Team Leadership: Lead develop and support managers and senior professionals; foster a culture of accountability collaboration and continuous improvement.
• Financial & Resource Stewardship: Support budget planning resource allocation and business case development for AI initiatives.

Core Competencies

• Enterprise AI & Digital Strategy
• Executive Presence & Influence
• Change Leadership & Resilience
• Ethical & Responsible AI Stewardship
• CrossFunctional Collaboration
• Program & Portfolio Management

This is a hybrid position and incumbent must live within 100 miles of the Rochester MN campus.

Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.

• Bachelors degree and 10 years of progressive experience in healthcare technology operations analytics or related fields with demonstrated leadership responsibility required.
• Masters degree and 10 years of progressive experience in healthcare technology operations analytics or related fields with demonstrated leadership responsibility preferred.
• Demonstrated experience leading high performing teams and delivering complex enterprise initiatives in a matrixed organizations preferred.