Contract – Senior Research Associate
South San Francisco, CA - USA
Job Summary
Cytokineticsis a specialty cardiovascular biopharmaceutical company building on its over 25 years of pioneering scientific innovations in muscle biology and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
We areseekinga highly motivated Research Associate with a focus on Drug Metabolism and Pharmacokinetics (DMPK) to join our team. The ideal candidate will contribute to our efforts inpharmacokineticsscreening plasma protein binding and microsomal assays.
This role offers an exciting opportunity to work in a collaborative and fast-paced environment supporting the development ofcutting-edgetherapies for cardiovascular and skeletal muscle disorders.
Responsibilities:
Bioanalysis:plasmaand tissue processing/analysis todeterminethe drug concentrationusing theSciexLC/MS-MS.
Plasma Protein Binding Studies: Conduct experiments todeterminethe binding affinity ofcompounds to plasma proteins usingSciexLC/MS-MS
Microsomal Assays:Perform microsomal stability studies to assessthe metabolicstability andrun the assay using theSciexLC/MS-MS
Data Analysis and Interpretation: Analyze experimental data usingappropriate software(WNL)andstatistical methods and provide clear and concise summaries of findings to support decision-making.
Documentation and Reporting:Maintaindetailed records of experimental procedures resultsand observations in laboratory notebooks and electronic databases. Prepare technical reportsand presentations for internal meetings and regulatory submissions.
Collaboration: Collaborate effectively with cross-functional teams including medicinal
chemistry pharmacology and toxicology to support drug discovery and development projects.
Lab Maintenance:Ensure proper maintenance and organization of laboratory equipmentreagents and supplies. Adhere to safety protocols andmaintaina clean and safe workingenvironment.
Qualifications:
Bachelors with 3 to 5 years of experience or Masters degree in Pharmaceutical Sciences Chemistry Biochemistry or a related field with 2 to 4 years.
Hands-on experience with DMPK assays including screening plasma protein binding and microsomal assays are preferred but not required.
Proven analytical and problem-solving skills with the ability to critically evaluate and interpret experimental data.
#LI-ONSITE
Pay Range:
In the U.S. the hiring pay range for fully qualified candidates is $54.30-$63.35 per hour. The base pay actually offered will take into account internal equity and also may vary depending on the candidates geographic region job-related knowledge skills and experience among other factors.Our employees come from different backgrounds and we celebrate those differences. We are looking for the best candidates for our open roles but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team we would love to hear from you.
Please review ourGeneral Data Protection Regulation (GDPR) policyPRIOR to applying.
Our passion is anchored in robust scientific thinking grounded in integrity and critical thinking. We keep the patient front and center in all we do all actions and decisions are in service of the patient and their caregivers. We champion integrity ethics doing the right thing and being our best selves.
Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
Recently there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain () and will only be made after completing a formal interview process.
Here are some ways to check for authenticity:
We do not conduct job interviews through non-standard text messaging applications
We will never request personal information such as banking details until after an official offer has been accepted and verified
We will never request that you purchase equipment or other items when interviewing or hiring
If you are unsure about the authenticity of an offer or if you receive any suspicious communication please contact us directly at
Cytokinetics is an Equal Opportunity Employer
Required Experience:
Senior IC