Computational Scientist II
South San Francisco, CA - USA
Job Summary
Job Duration: Long Term Contract (Possibility Of Extension)
We are seeking a Computational Scientist II to join Genentechs Developmental Sciences organization and help advance AI-driven drug this role you will design develop and deploy LLM-powered agentic workflows that automate scientific processes within Clinical Pharmacology and Pharmacometrics. You will collaborate with scientists pharmacometricians and AI engineers to build production-ready AI solutions develop evaluation frameworks integrate scientific knowledge into AI systems and improve the efficiency of quantitative drug development.
- Design develop and deploy LLM-based agentic AI workflows to automate scientific and pharmacometric processes.
- Build RAG (Retrieval-Augmented Generation) pipelines human-in-the-loop AI systems and reusable LLM components.
- Develop evaluation frameworks guardrails and quality control processes for LLM outputs.
- Collaborate with pharmacometricians clinical pharmacologists data scientists and software engineers to translate scientific requirements into AI solutions.
- Integrate scientific guidelines templates and reference documents into AI workflows.
- Develop production-ready software following best engineering practices including Git documentation code reviews and testing.
- Support deployment of AI applications on cloud platforms (AWS Azure or GCP).
- Present technical solutions documentation and best practices to cross-functional stakeholders.
- Bachelors degree with 5 years of experience or Masters/PhD in Computer Science Data Science Bioinformatics Computational Biology Pharmaceutical Sciences or a related quantitative field.
- Experience developing LLM applications Agentic AI systems or Generative AI solutions.
- Strong programming experience with Python and software engineering best practices.
- Experience with LangChain LangGraph LangSmith RAG architectures vector databases and LLM APIs.
- Knowledge of Git CI/CD code reviews testing and documentation.
- Experience with cloud platforms (AWS Azure or GCP).
- Excellent communication and collaboration skills.
- Experience in pharmaceutical biotech computational biology pharmacometrics or drug discovery.
- Experience developing AI solutions for scientific or regulated environments.
- Familiarity with evaluation frameworks LLM guardrails prompt engineering and human-in-the-loop workflows.
- Experience working with structured and unstructured scientific data.
- Portfolio of AI/LLM projects or open-source contributions.
- Large Language Models (LLMs)
- Agentic AI & Generative AI
- LangChain LangGraph LangSmith
- Retrieval-Augmented Generation (RAG)
- Python Programming
- AI Workflow Automation
- AWS / Azure / GCP
- Computational Biology / Bioinformatics
- Drug Discovery & Pharmaceutical R&D
- Data Science & Machine Learning
If interested please send us your updated resume at
Required Skills:
RAG Architecture LLM Agentic AI Computational Biology