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Computational Scientist II


Job Location:

South San Francisco, CA - USA

Salary: Not provided by the employer
Posted: 26 June 2026 (30+ days ago)
Application Deadline: 23 September 2026
Vacancies: 1 Vacancy

Job Summary

Our Client a world leader in Biotechnology is looking for a "Computational Scientist II" for SSF CA


Job Duration: Long Term Contract (Possibility Of Extension)

Pay Rate: $48 - $49/hr on W2
Company Benefits: Medical Paid Sick leave 401K

We are seeking a Computational Scientist II to join Genentechs Developmental Sciences organization and help advance AI-driven drug this role you will design develop and deploy LLM-powered agentic workflows that automate scientific processes within Clinical Pharmacology and Pharmacometrics. You will collaborate with scientists pharmacometricians and AI engineers to build production-ready AI solutions develop evaluation frameworks integrate scientific knowledge into AI systems and improve the efficiency of quantitative drug development.

Responsibilities
  • Design develop and deploy LLM-based agentic AI workflows to automate scientific and pharmacometric processes.
  • Build RAG (Retrieval-Augmented Generation) pipelines human-in-the-loop AI systems and reusable LLM components.
  • Develop evaluation frameworks guardrails and quality control processes for LLM outputs.
  • Collaborate with pharmacometricians clinical pharmacologists data scientists and software engineers to translate scientific requirements into AI solutions.
  • Integrate scientific guidelines templates and reference documents into AI workflows.
  • Develop production-ready software following best engineering practices including Git documentation code reviews and testing.
  • Support deployment of AI applications on cloud platforms (AWS Azure or GCP).
  • Present technical solutions documentation and best practices to cross-functional stakeholders.
Required Qualifications
  • Bachelors degree with 5 years of experience or Masters/PhD in Computer Science Data Science Bioinformatics Computational Biology Pharmaceutical Sciences or a related quantitative field.
  • Experience developing LLM applications Agentic AI systems or Generative AI solutions.
  • Strong programming experience with Python and software engineering best practices.
  • Experience with LangChain LangGraph LangSmith RAG architectures vector databases and LLM APIs.
  • Knowledge of Git CI/CD code reviews testing and documentation.
  • Experience with cloud platforms (AWS Azure or GCP).
  • Excellent communication and collaboration skills.
Preferred Qualifications
  • Experience in pharmaceutical biotech computational biology pharmacometrics or drug discovery.
  • Experience developing AI solutions for scientific or regulated environments.
  • Familiarity with evaluation frameworks LLM guardrails prompt engineering and human-in-the-loop workflows.
  • Experience working with structured and unstructured scientific data.
  • Portfolio of AI/LLM projects or open-source contributions.
Key Skills
  • Large Language Models (LLMs)
  • Agentic AI & Generative AI
  • LangChain LangGraph LangSmith
  • Retrieval-Augmented Generation (RAG)
  • Python Programming
  • AI Workflow Automation
  • AWS / Azure / GCP
  • Computational Biology / Bioinformatics
  • Drug Discovery & Pharmaceutical R&D
  • Data Science & Machine Learning

If interested please send us your updated resume at

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Required Skills:

RAG Architecture LLM Agentic AI Computational Biology