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Associate Director, Heme Global Business Systems


Job Location:

Boston, MA - USA

Yearly Salary: USD 162800 - 244200
Posted: 16 June 2026 (30+ days ago)
Application Deadline: 8 December 2026
Vacancies: 1 Vacancy
The job posting is outdated and position may be filled

Job Summary

Job Description

About Vertex:At Vertex we are relentless in our pursuit of transformative medicines to improve the lives of people with serious on a strong foundation of advancing therapies for cystic fibrosis Vertex continues to expand its leadership across multiple disease areas including cell and gene therapies with the goal of delivering meaningful impact for patients worldwide.

Our Global Heme Cell and Gene Therapy (CGT) Operations team is at the forefront of innovation commercial strategy and operational excellence driving the evolution of the global cross-functional vein to vein business process for CASGEVY the only CRISPR-based autologous gene therapy approved for people living with Sickle Cell Disease and Transfusion dependent beta thalassemia.

Position Summary:

We areseeking an Associate DirectorHemeCGTBusiness Systemsto lead global system strategy for CASGEVY. This critical role will beresponsible for owning the strategy roadmap and execution of the order management system and key commercial tools and processes essentialto delivering a vein-to-vein autologous CASGEVY continues to scale across 9 markets globally the successful candidate willbring a strategic analytical and collaborative mindsetprovide cross-functional leadershipand drivealignmentamonginternationaland USHeme Business Units Manufacturing Quality and Technology teamsinvolved in CASGEVY delivery.

Key Responsibilities:

  • Own the product vision roadmap and prioritization for commercial capabilities supporting the Heme Franchise
  • Partner with IT and regional stakeholders to translate business priorities into scalable tools processes and product enhancements
  • Drive cross-functional alignment across global commercial teams external manufacturing quality and other enabling functions to support business objectives governance and effective decision-making
  • Work closely with Quality to ensure appropriate GxP processes controls and requirements are understood and adhered to across relevant systems tools and processes
  • Lead change management efforts to support successful implementation stakeholder engagement and adoption of commercial capabilities across the organization
  • Drive continuous improvement and ongoing optimization of commercial capabilities to enhance planning execution and operational effectiveness

Qualifications

  • Demonstrated success working in cross-functional matrixed organizations with multiple stakeholders
  • Strong ability to simplify high-level concepts into actionable insights and advise on digital maturity digital transformation and system integrations to the site leadership team
  • Analytical problem-solving and strategic planning abilities

Education and Experience:

  • Bachelors degree in relevant discipline
  • Typically requires 8 years of work experience leading the delivery of customer facing digital programs to promote products and services to external customers or the equivalent combination of education and experience
  • Experience in GxP regulated systems and related documentation and GxP process and change management is highly preferred

Location:Boston
Flex Designation:On-site/Hybrid

Why Join UsAt Vertex youll be part of a team that is transforming the lives of patients through innovative therapies. We offer a dynamic and inclusive work environment where your contributions will make a meaningful impact.

How to Apply:If you are a driven professional with a passion for operational excellence and process optimization we encourage you to apply. Please submit your resume and cover letter through ourcareersportal.


At Vertex we embrace continuous learning and encourage employees to stay informed on advances in AI technology automation and industry trends. We seek talent who bring an external perspective demonstrate curiosity and sound judgment and thoughtfully adopt new capabilities that improve decision-making drive innovation increase efficiency and help deliver better outcomes for patients.

Pay Range:

$162800 - $244200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.

At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at


Required Experience:

Director


About Company

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Vertex Pharmaceuticals invests in scientific innovation to create transformative medicines for people with serious diseases.

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