Associate Director FP&A, Clinical Accounting & Data Analysis

Job Description

Associate Director FP&A - Clinical Accounting & Data Analysis

About Vertex Pharmaceuticals

Vertex is a global biotechnology leader transforming lives through groundbreaking science. Weve revolutionized treatment for cystic fibrosis and are applying the same rigorous innovation to sickle cell disease beta thalassemia and other serious conditions. Our culture champions bold thinking scientific excellence and genuine impactwhere your work directly improves patient lives.

Join a team where exceptional talent meets purpose-driven innovation in an environment that values both professional growth and work-life integration.

The Opportunity

Lead the strategic evolution of our Clinical Center of Excellence (CCoE) as Associate Director FP&A - Clinical Accounting & Data Analysis. This is a high-impact role at the intersection of finance analytics and clinical operationswhere youll shape how Vertex plans forecasts and manages a multi-billion dollar clinical portfolio.

Youll architect the financial intelligence framework that guides critical investment decisions across our pipeline leading a team of two talented professionals while partnering with senior leaders across Finance Clinical Operations and beyond. This role is ideal for a strategic finance leader who thrives on complexity drives operational excellence and sees data as a catalyst for transformational insight.

What Youll Do

Drive Strategic Financial Leadership

• Shape the financial narrative for Global Clinical Operations translating complex clinical and financial data into executive-ready insights that drive portfolio decisions
• Build and refine KPIs that mattermetrics that predict outcomes identify risks early and unlock investment opportunities across our clinical pipeline
• Partner with senior leadership to scenario-plan our clinical future: where to accelerate where to optimize and how to maximize strategic value

Own the Analytical Engine

• Lead evolution of our clinical trial accrual and forecasting modelsdriving accuracy automation and scalability as our portfolio grows
• Generate predictive insights from integrated clinical and financial data: enrollment trends cost drivers timeline risks and resource optimization opportunities
• Deliver variance analysis and forward-looking scenarios that move beyond reporting to true decision support

Orchestrate Cross-Functional Excellence

• Influence without authority across Clinical Operations Accounting Reporting and HR to align assumptions drive accountability and ensure financial discipline
• Serve as the trusted finance partner clinical leaders turn to for strategic guidance and operational problem-solving
• Collaborate with our Reporting & Analytics CoE to pioneer AI and emerging technologies that transform how we work

Ensure Financial Integrity & Controls

• Oversee monthly/quarterly close activities for clinical expenses with precision and efficiency
• Maintain bulletproof audit readiness through robust SOX controls comprehensive documentation and proactive risk management
• Champion GAAP compliance and governance excellence across all clinical accounting processes

Build & Develop Your Team

• Coach and mentor two direct reports fostering technical depth strategic thinking and business acumen
• Create a culture of continuous improvement where innovation learning and healthy challenge are celebrated
• Design roles and responsibilities that scale with business needs while accelerating career growth

What You Bring

Required Experience & Expertise

• 8 years in FP&A accounting or finance business partnering with progressive responsibility
• Clinical finance expertise: Deep understanding of clinical trial lifecycles cost structures enrollment dynamics and R&D financial management
• Technical accounting mastery: GAAP clinical trial accruals journal entries reconciliations month-end/quarter-end close and SOX compliance
• Leadership experience: Proven track record developing talent coaching high performers and building team capabilities
• Influence & impact: Demonstrated ability to drive outcomes across functions through strategic partnership clear communication and credibility

Technical Skills

• Advanced financial modeling (clinical accruals forecasting scenario planning)
• Variance analysis and KPI development
• Financial systems fluency (ERP planning tools reporting platforms)
• Advanced Excel proficiency
• Executive communication and presentation skills

Education

• Bachelors degree in Finance Accounting Economics or related field

What Sets You Apart

• MBA CPA CFA or advanced finance/accounting credential
• Biotech/pharma experience: Understanding of CRO relationships clinical trial agreements and regulatory milestones
• Systems expertise: SAP Anaplan Oracle Hyperion or similar enterprise planning platforms
• Analytics mindset: Experience with data visualization tools (Tableau Power BI) and process automation
• Innovation orientation: Curiosity about AI machine learning and emerging technologies that can transform finance operations
• Strategic thinking: Ability to see around corners anticipate challenges and proactively solve problems before they arise

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#LI-MF1

Why This Role Why Vertex

Impact That Matters Your financial strategies directly influence which therapies reach patients and how efficiently we operate. This isnt finance for finances sakeits finance in service of saving lives.

Complexity Youll Love Navigate the intersection of science business and finance in one of the most dynamic industries. No two days are the same.

Growth & Learning Work alongside world-class talent. Access cutting-edge tools and technologies. Continuously expand your capabilities.

Culture of Excellence We set high standards and support each other in meeting them. We celebrate wins learn from setbacks and always push forward together.

Comprehensive Benefits Competitive compensation equity participation health and wellness programs generous PTO parental leave 401(k) match and more.

Our Commitment to Inclusion

Vertex is committed to equal employment opportunity and does not discriminate based on race color religion sex sexual orientation gender identity national origin protected veteran status disability or any other legally protected status.

We believe diverse perspectives make us stronger. We actively seek candidates from all backgrounds who share our passion for innovation and patient impact.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at