Associate Director, Digital Proteomics and AI Innovation

Make a meaningful impactonpatients lives around theworld

At AstraZeneca we are combiningcutting-edgesciencedataand artificial intelligence to transform how we discover and develop medicines. This role sits within the Centre for Genomics Research (CGR) and works in close collaboration with AstraZeneca Infectious Disease and Oncology offering a unique opportunity to shape new digital and AI capabilities for the cancer vaccine space.

Based in CGR you will sit at the intersection of mass spectrometry-based proteomicsimmunopeptidomicsand agentic AI building the data foundations and intelligent systems that allow scientists to explore high-throughput proteomics HLA-peptidomics neoantigen discovery genetic sequencing transcriptomics and emerging molecular assays as a connected whole. This is a hands-on technical role for someone who can combine deep proteomicsexpertisewith the practical engineering judgement needed to designdeployand scale AI systems that scientific usersactually relyon.

Whatyoulldo

As Associate Director Digital Proteomics and AI Innovation within CGR you will:

• Identifyhigh-value workflow opportunitieswhere agentic AI can transform how proteomicpeptidomicand multi-omicdata are explored integratedinterpretedand automated.

• Design build deploy and iterateAI-enabled systems including agentic workflows that are usablemaintainableand integrated into real scientific practice.

• Bring deep domainexpertisein mass spectrometry proteomics andpeptidomicsto shape data standards analyticalapproachesand biological interpretation withparticular relevancetoimmunopeptidomicsand neoantigen-centric workflows.

• Drive integrative analysisacross proteomicspeptidomics sequencingtranscriptomicsand experimental metadata to generate translational insight.

• Partner withinformaticiansdata andmass spectrometry scientistswithin CGR and collaborate closely with scientific stakeholders in AstraZeneca Infectious Disease and Oncology to embed AI capabilities into scalable governed analytical environments.

• Contribute technicalexpertiseto scientific discussions sharing knowledge with colleagues and engaging with internal and external scientific communities.

Essential criteria

• Advanced degree (PhD or equivalent experience) in proteomics computational biology bioinformatics data science biostatistics computerscienceor a related discipline.

• Deepexpertisein mass spectrometry-based proteomics andpeptidomics including a working understanding of experimental design data characteristicslimitationsand interpretation challenges.

• Strong hands-on data science and software delivery experience witha track recordof buildingdeployingandmaintaininganalytical or AI-enabled systems used by scientific teams.

• Demonstrated experience developing agentic AI workflows or advanced AI systems for scientific data explorationinterpretationor workflow automation.

• Proven ability to integrate and analyse multidimensional datasets spanning proteomicspeptidomics sequencingtranscriptomicsand associated metadata to generate biological insight.

• Ability tooperateas an independent hands-on technical contributor combining scientific judgement with pragmatic engineering and delivery.

• Excellent communication and collaboration skills witha track recordof translating complex scientific and technical concepts into solutions that scientific and technical users adopt.

Desirable criteria

• Experience applying digital proteomics and AI-enabled approaches in oncology immunology cancer vaccinesimmunopeptidomicsor neoantigen discovery.

• Experience designing data foundations ontologies harmonised analyticalenvironmentsor reusable AI capabilities for large-scale scientific research.

• Experience extending acrossadditionalomics modalities in partnership with domain specialists.

• Track recordof innovationevidencedthrough deployed tools software products open-source contributions peer-reviewedpublicationsor conference presentations in proteomicspeptidomics AI or data science.

How we do it

At AstraZenecawerededicated to being a Great Place to Work where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit.Theresno better place to make a difference in medicine patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning growth and development.