Applications Scientist

Oxford Nanopore Technologies (ONT) is transforming the way scientists and researchers analyze DNA and RNA through real-time accessible sequencing technology. Our innovative nanopore platform enables breakthroughs across research clinical genomics infectious disease oncology and many other fields.

We are looking for an enthusiastic and collaborative Applications Scientist to join our Commercial Applications team in Alameda California. This is an exciting opportunity for an early-career scientist who enjoys hands-on laboratory work customer collaboration and solving complex scientific challenges using cutting-edge sequencing technologies.

The Opportunity

As an Applications Scientist you will support strategic customer collaborations by designing and executing wet lab experiments generating high-quality nanopore sequencing data and partnering with bioinformatics commercial and R&D teams to deliver meaningful scientific outcomes.

Youll work across a wide variety of applications including:

• Rare and undiagnosed diseases
• Oncology
• Metagenomics
• Single-cell and spatial biology
• Multiomics
• Whole genome sequencing
• Transcriptomics
• Targeted sequencing
• Adaptive sampling

This role offers an excellent opportunity to broaden your expertise across diverse sequencing applications while working directly with customers and internal scientific experts.

What Youll Do

Experimental Design & Laboratory Research

• Design and execute sequencing experiments including library preparation strategies and sequencing workflows.
• Generate high-quality nanopore sequencing data from diverse sample types.
• Perform molecular biology techniques including:
  • DNA and RNA extraction
  • Library preparation
  • PCR
  • Fragmentation and size selection
  • Library quality control
  • Cell culture
• Troubleshoot technical challenges related to sample preparation library construction multiplexing strategies and sequencing performance.

Customer & Scientific Collaboration

• Partner with customers and internal teams to support strategic research collaborations.
• Provide technical guidance on sequencing workflows laboratory best practices expected yields and read-length optimization.
• Collaborate closely with bioinformatics scientists to analyze and interpret sequencing results.
• Contribute scientific expertise across multiple nanopore sequencing applications.

Scientific Communication

• Prepare technical reports presentations posters application notes and other customer-facing materials.
• Clearly communicate project outcomes and recommendations to customers and internal stakeholders.

Laboratory Operations

• Maintain laboratory inventory including reagents consumables sequencing flow cells and supplies.
• Ensure laboratory activities comply with quality standards safety procedures and operational best practices.

What Youll Bring

Required Qualifications

• Bachelors degree in Molecular Biology Biochemistry or a related Life Science discipline with 13 years of industry experience or
• Masters degree in Molecular Biology Biochemistry or a related field.
• Strong wet lab molecular biology experience gained through academic or industry research.
• Solid understanding of molecular biology principles and experimental design.
• Excellent troubleshooting and critical thinking skills.
• Strong written and verbal communication abilities.
• Ability to manage multiple projects in a collaborative fast-paced environment.

Preferred Qualifications

• Experience with next-generation sequencing (NGS) particularly long-read sequencing technologies.
• Experience working directly with customers or external collaborators.
• Familiarity with bioinformatics tools and computational analysis.
• Experience using Linux command-line interfaces (CLI) HPC environments Python R or data analysis workflows.

• Knowledge of genomics applications including transcriptomics metagenomics targeted sequencing or whole genome sequencing.

  
  

Please note that no terminology in this advert is intended to discriminate on the grounds of a persons gender marital status race religion colour age disability or sexual orientation. Every candidate will be assessed only in accordance with their merits qualifications and abilities to perform the duties of the job.

The salary for this role is between $82400and $103000USD. The salary offered will reflect the skills and experience of the candidate.

Certain roles within ONT are eligible for annual bonus and stock. These awards are allocated based on individual performance.

Employees based in the US have the option to choose healthcare benefits participate in the company 401(k) plan and company match we also offer short-term and long-term disability coverage basic life insurance and commuter benefits to name a few.

We are proud to be an equal opportunity employer. We select and employ candidates only in accordance with their merits qualifications and abilities to perform the duties of the job regardless of gender marital status race religion color age disability sexual orientation military or veteran status. If you require an accommodation to complete the application or interview process please contactTo learn more visit: Experience:

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