Student Internship on Gene Therapy Bioassay and Formulation Development in Pharmaceutical Development (Basel, 6-12 months)

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In Roches PTD Biologics Pharmaceutical Development (PTDP) we are responsible for the technical development and preparation of sterile dosage forms of biotechnologically and chemically engineered molecules including gene therapies.

We are now offering a unique opportunity to join our team in Basel and contribute to the formulation development of novel gene therapies by supporting protocol and sample preparation for laboratory activities performing advanced analytics to assess the quality attributes of the prepared formulations and a particular focus on setting up and executing a cell-based functional assay.

If you are curious willing to learn and work in a highly collaborative and supportive international team environment we are looking forward to receiving your application.

As an intern in our team your responsibilities will include:

• Working safely and responsibly in a BSL-2 laboratory environment handling mammalian cells and recombinant adeno-associated viral vectors (rAAVs)

• Carrying out day-to-day cell culture activities

• Establishing a cell-based assay to assess the stability of rAAV formulations

• Learning and performing relevant analytics such as dd/qPCR flow cytometry HPLC DLS etc and the associated preparatory procedures such as RNA isolation

• Planning your studies in line with the concurrent needs and timelines and preparing your protocols

• Performing experiments recording analysing and presenting your data to the local and broader teams

• Opportunity to engage in departmental activities related to innovative formulations processes and technologies

• You must either be currently enrolled at a university in pharmaceutical sciences chemistry biotechnology chemical engineering mechanical engineering biology or a related field pursuing a Bachelors or Masters degree; or have completed your studies (passed the 2nd state examination of your pharmacy studies) within the past 12 months prior to the starting date with a Bachelors or Masters degree.

• Cell culture experience and experience of working in the lab without direct supervision (e.g. on a research project) is necessary

• Previous experience with molecular and/or biophysical analytical methods used in gene therapy formulation development is desirable

• Demonstrate efficient time management planning and appropriate record-keeping with previous experience using electronic lab books being desirable.

• Understand data analysis and experience analyzing data using MS Excel Google Sheets GraphPad Prism R JMP or other analysis software would be an advantage.

• Bring curiosity adaptability willingness to learn and support the team collaborative spirit openness to different working styles.

• Work independently on small projects in the laboratory and/or support challenging aspects of ongoing projects.

• Build technical documentation present results in internal meetings learn how current industrial requirements are implemented in everyday life and gain insights into the multifaceted and diverse working environment of pharmaceutical development.

• Preferred start date: September 2026; please clearly indicate your availability for the internship (min. 6 months) in your cover letter.

• Applications need to include a CV and a motivation letter.

• For Non-EU/EFTA citizens: due to regulations you must provide a mandatory letter issued by your university stating that an Internship is mandatory for your studies (for both 6 months and longer). For an internship lasting longer than 6 months it also needs to specify the required length of the internship. Please upload this mandatory letter and your enrollment certificate along with your CV and motivation letter.

Ready to take the next step Wed love to hear from you. Apply now to explore this exciting opportunity!

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Roche is an Equal Opportunity Employer.