Repository Technician

Fred Hutchinson Cancer Center is an independent nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation HIV/AIDS prevention immunotherapy and COVID-19 vaccines Fred Hutch has earned a reputation as one of the worlds leading cancer infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology infusion radiation proton therapy and related services and network affiliations with hospitals in five states. Together our fully integrated research and clinical care teams seek to discover new cures to the worlds deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration compassion determination excellence innovation integrity and respect. Our mission is directly tied to the humanity dignity and inherent value of each employee patient community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Repository Technician is responsible for maintaining the laboratory biospecimen repository managing laboratory equipment and ensuring strict compliance with Good Clinical Laboratory Practice (GCLP) standards. This operational role involves hands-on specimen accessioning storage retrieval inventory reconciliation and chain-of-custody documentation to ensure the absolute integrity and traceability of biological specimens.

Repository (50%)

• Oversee the day-to-day operation and organization of the laboratory specimen repository ensuring specimen integrity traceability and uninterrupted cold chain management within liquid nitrogen and 80C storage systems.
• Maintain accurate specimen inventories and records within the Laboratory Information Management System (LIMS) ensuring timely data entry inventory reconciliation system updates and liaison with laboratory staff and vendors as required.
• Coordinate specimen requests and perform hands-on retrieval accessioning storage shipment preparation and distribution of specimens for internal testing and external collaborators ensuring timely communication of sample availability shipment schedules and any discrepancies.
• Generate and/or quality control (QC) Master Thaw Lists (MTLs) and Individual Thaw Lists (ITLs) to support laboratory testing activities.
• Monitor repository capacity and implement strategies to optimize storage utilization including repository reorganization specimen consolidation archival activities and disposition of expired or obsolete specimens.
• Receive package ship and document biological specimens in accordance with IATA regulations GCLP requirements sponsor requirements and laboratory SOPs.
• Track CTAC sample controls competency panels locked specimens and specimens designated for ICS QFT and other laboratory assays liaising with internal and external stakeholders as required.
• Maintain and ensure timely submission of all required specimen inventory reports and regulatory documentation to the Department of Health.
• Serve as the main liaison for the laboratory and repository related issues or process improvements.
• Serve as the document owner for repository-related SOPs ensuring procedures remain current and conducting staff training on repository processes as required.

Equipment Maintenance (20%)

• Coordinate the repository maintenance calibration qualification and servicing of laboratory equipment to ensure operational readiness and continued compliance with GCLP and laboratory quality standards.
• Monitor repository equipment performance maintenance schedules service records and associated documentation identifying trends and coordinating corrective actions where necessary.
• Coordinate repository equipment procurement repairs troubleshooting and vendor service visits as required.
• Liaise with suppliers to ensure the continuous availability of liquid nitrogen dry ice gases and other critical laboratory consumables.
• Provide general support and backup support for all other laboratory equipment maintenance calibration qualification and servicing from designee.
• Maintain equipment-related SOPs and provide training to laboratory personnel on equipment operation and maintenance requirements.
• Ensure laboratory equipment and associated activities comply with institutional safety policies and regulatory requirements.

Laboratory Operations and Safety (20%)

• Serve as the Laboratory Safety Officer promoting compliance with laboratory safety policies GCLP and Environmental Health and Safety (EHS) requirements.
• Provide On-call and after-hours laboratory support by responding to urgent issues and ensuring continuity of critical lab operations and equipment.
• Conduct laboratory risk assessments safety inspections and follow-up activities to ensure a safe working environment.
• Support compliance of the specimen repository and specimen processing laboratory with institutional and regulatory safety requirements.
• Coordinate and deliver laboratory safety training and maintain associated training records.

GCLP Compliance (10%)

• Perform quality control reviews of repository equipment and safety documentation to ensure compliance with GCLP laboratory SOPs and applicable regulatory requirements.
• Draft review revise and maintain laboratory SOPs and controlled documents within the quality management system.
• Prepare maintain and organize documentation required to support internal audits external audits inspections and sponsor visits.
• Represent repository equipment and safety functions during internal and external audits implementing corrective and preventive actions (CAPAs) where applicable.

Other duties as assigned.

Education Certification Qualifications and Experience Needed

• Bachelors degree or BTech in a relevant field (e.g. Biomedical Technology) or equivalent diploma/Medical Technician certification (Chemical/Clinical Pathology Haematology Microbiology or Immunology).
• Minimum 5 years experience in a GCLP-compliant or similarly auditable laboratory environment within South Africa.
• Proven experience with LIMS for specimen management; familiarity with LDMS and LabWare advantageous.
• Valid IATA certification for international biological specimen shipments.
• Demonstrate experience in cold-chain management specimen processing and laboratory operations.
• Strong coordination skills to support efficient specimen handling and transfer within a South African healthcare/research setting.
• Hands-on experience troubleshooting laboratory equipment and managing vendor/service provider relationships.
• Proficient in MS Office (advanced Excel); experience with document management systems (e.g. SharePoint Veeva) preferred.

Competencies and Job Specifications Required to do the Job

• Strong knowledge of Quality Assurance Quality Control and GCLP laboratory standards.
• High attention to detail in laboratory processes documentation and SOP compliance.
• Organised methodical approach to hands-on lab work with the ability to guide and support others.
• Effective communication and interpersonal skills with proven ability to collaborate within multidisciplinary and international teams in a South African research environment.
• Self-motivated and able to work independently manage multiple priorities and meet deadlines.
• Adaptable and flexible in a dynamic fast-paced environment with a continuous improvement mindset.
• Sound judgment and decision-making skills with the ability to respond effectively under pressure.

Protection of Personal Information Act (POPIA) Consent to Use and Collection of Personal Information Including Consent to Background Check.