Senior Technical Product Cell & Gene Therapies

We are searching for the best talent for Senior Technical Product Manager R&D Therapeutics Development Cell & Gene Therapies to be in Malvern PA Spring House PA or Leiden Netherlands.

Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings we recommend focusing on the specific country(s) that align with your preferred location(s):

US Requisition Number: R-090524

Remember whether you apply to one or all of these requisition numbers your applications will be considered as a single submission.

In this role the Sr. Technical Product Manager (TPM) will lead the technology strategy and roadmap for the Cell & Gene Therapies (CGT) department within the Therapeutics Development (TDS) organization delivering scalable data-driven solutions that accelerate product development while ensuring compliance and quality. You will collaborate closely with business partners with a shared goal to develop the best compound and administration vehicle and produce the best product and associated manufacturing process right first time.

The Sr. TPM will be part of the Innovative Medicine Technology R&D Research Systems team. The objective of the Research Systems team is to deliver cutting-edge technological solutions that empower our R&D partners within JJIM. Our aim is to facilitate the creation of innovative solutions that effectively address crucial unmet medical needs. Our targets are pressing needs in oncology immunology and neuroscience among others.

To achieve the JJIM R&D goal of increasing the number of internally originated drugs brought to the market it is necessary to enable expedited exploration of a larger and more diverse molecular space. This can be achieved through the implementation of automation utilization of novel modalities profiling approaches and the application of data science. The success of these endeavors is dependent on the presence of technology platforms that facilitate automated laboratory systems seamless integration and analysis of generated data and provide valuable insights and decision-making support to researchers.

We are looking for a candidate who is bi-lingual in science and IT who can collaborate with business and IT partners to deliver effective scientific IT solutions for our organization. A foundational understanding of the drug discovery process is essential for this role.

The ideal candidate will be proactive possess a strong problem-solving mindset and demonstrate the ability to manage stakeholders in a fast-paced dynamic work environment.

Key responsibilities

• Define and lead the product roadmap for the CGT organization.

• Translate scientific and operational needs into actionable product requirements; manage the backlog and drive value-focused delivery.

• Forge strong partnerships with Innovative Medicine Technology R&D Research Systems J&J Technology Services Quality and external vendors to deliver integrated automation and digital solutions supporting advanced therapies workflows.

• Lead end-to-end data strategy: data capture governance quality lineage and analytics consumption to enable informed decision-making.

• Ensure seamless interoperability across the digital ecosystem bridging the gap between discovery data development platforms and downstream clinical supply/execution systems.

• Drive Agile-powered delivery with cross-functional squads; ensure features are delivered on time within budget and to quality standards.

• Oversee vendor selection integration and performance management for automation hardware and software solutions.

• Promote a data-literate culture and enable self-service analytics for lab users with secure access and appropriate governance.

• Lead change management training and documentation to drive adoption across global sites.

• Ensure compliance with GxP data integrity standards and quality-by-design.

• Operate with a global mindset coordinating activities across sites and regions; participate in occasional travel as needed.

Qualifications

Education

• Masters degree preferred; bachelors degree with substantial relevant experience acceptable.

• Relevant certifications (e.g. PMI product management Agile GMP/GCP AWS ) are a plus.

Experience and skills

• A minimum of a bachelors degree in information technology bioinformatics pharmaceutical sciences or related subject area is required or demonstrable experience to work with informatics and scientific IT applications. A masters degree is preferred.

• 5 years of experience supporting digital/IT capabilities within a biologics cell-therapy or gene therapy scientific environment.

• Good understanding of advanced therapy medicinal products (CAR-T mRNA viral vectors ).

• Knowledge of the different workflows for autologous allogeneic and in vivo therapies.

• Familiarity with cell processing and analytics (cell isolation expansion analytical characterization).

• High-level understanding of pipelines used to process genomic transcriptomic and proteomic data.

• Familiarity with core lab IT/OT systems (LIMS ELN) and automation/processing hardware (e.g. cell processing systems bioreactors analytical instrumentation).

• Experience delivering data-enabled solutions: data governance data integration analytics and data quality across laboratory environments.

• Strong critical thinking with the ability to translate scientific and operational goals into a technology roadmap.

• Excellent leadership and cross-functional collaboration skills; comfortable operating in a matrixed global environment.

• Agile/SAFe experience and a track record of delivering large-scale technology programs.

• Outstanding communication and stakeholder management; ability to influence senior leaders and diverse teams.

• Demonstrated adaptability problem-solving and the ability to inspire change in scientific and manufacturing contexts.

Required capabilities or differentiators

• Global cross-site program leadership with experience in (regulated) labs.

• Proven track record to partner with R&D Clinical IT and external suppliers to deliver integrated solutions.

• Strong emphasis on data-driven decision-making and measurable outcomes (return on investment adoption time-to-value).

• Change management user enablement and training to drive adoption of new lab automation capabilities.

Travel

• Up to 1020% travel anticipated (adjustable based on project needs and policy).

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Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please contact us via or contact AskGS to be directed to your accommodation resource.