Biologics Process Research & Development Scientist

Job Description

Biologics Process Research & Development (BPR&D) within our Companys Research Laboratories is on a mission to rapidly deliver biotherapeutics to patients by efficiently developing innovative robust manufacturing processes and technologies. To achieve this we work closely with colleagues in Discovery Pre-clinical Early Development Analytical Formulation and Commercial Manufacturing while providing an inclusive environment for all. Beyond process development for pipeline biologics we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing green and sustainable processes and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.

Biologics Process Research & Development (BPR&D) includes three lab-facing technical functional areas: Process Cell Sciences (PCS) Upstream Process Development (UPD) and Downstream Process Development & Engineering (DPDE). This job posting covers opportunities for all three functional areas. We are actively looking for highly motivated people with a passion for innovation and interest in contributing to one or more of the three technical functional areas mentioned above.

As a Scientist in Biologics Process Research & Development (BPR&D) you will work with immensely creative and collaborative team members to design and develop robust processes in support of early- and late-stage biologics. You will innovate to support our companys biologics pipeline and production platforms through rigorous scientific principles. You will have the opportunity to apply and integrate innovation into biologic process sciences to establish our company as the industry leader in next-generation biologics manufacturing. You may also be expected to contribute to additional areas of interest such as biophysical reactor process economic and/or multivariate modeling as we are committed to leveraging digital ways of working to enhance our ability to design robust processes.

Responsibilities include but are not limited to:

Develop innovative and disruptive technologies for next-generation biologics manufacturing processes

Develop and characterize robust clinical processes capable of delivering multi-kilogram quantities of therapeutics

Design and conduct experiments related to cell-line development upstream or downstream bioprocessing

Integrate unit operations with relevant process control and monitoring platforms

Collaborate across Biologics Process Research & DevelopmentBPR&D process analytics and other functional areas in research and manufacturing to advance the biologics pipeline

Conduct laboratory- and/or pilot-scale studies to support scale-up and technology transfer to manufacturing sites

Contribute to a safe and compliant laboratory work environment

MINIMUM EDUCATION REQUIREMENTS:

Education:

Bachelors Degree with 2 years of relevant experience or masters degree in chemical/Biochemical/Biomedical Engineering Biotechnology Biochemistry Molecular Biology or related fields with research background in molecular biology cell culture or protein purification

REQUIRED EXPERIENCE AND SKILLS:

Experience with one or more of molecular biology protein expression mammalian cell culture protein purification biochemical engineering or analytical technologies

Scientific understanding of the engineering principles behind recombinant protein production and purification

Ability to comprehend and execute experiments independently

Ability to organize communicate analyze and present experimental data to drive conclusions and further study designs

Knowledge of aseptic technique protein biophysical properties and general protein laboratory practices

Demonstrated ability to independently prepare technical documents and scientific presentations to capture development progress scientific investigations and technology development output

Basic understanding of statistical methods and data analysis tools

Strong passion and commitment to integrate science and innovation into biologic process development

Ability to excel in a collaborative and matrix environment

PREFERRED EXPERIENCE AND SKILLS:

Demonstrated capabilities in understanding and operating bioanalytical techniques to characterize microbial or cell culture processes

Ability to think critically with excellent problem solving and troubleshooting skills

High throughput screening automated bioreactor systems and liquid handlers

Experience with process transfer to clinical or commercial manufacturing facilities

Knowledge of process control and workflow automation tools

Strong foundation in statistical analysis design of experiments data science computational modeling

#BPRD #PRD

Required Skills:

Preferred Skills:

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U.S. Hybrid Work Model

Effective September 5 2023 employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week Monday - Thursday although the specific days may vary by site or organization with Friday designated as a remote-working day unless business critical tasks require an on-site Hybrid work model does not apply to and daily in-person attendance is required for field-based positions; facility-based manufacturing-based or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

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