Sr. Scientist, Viral Vector

Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But were not finished yet.

Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.

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Job Description

Kite Pharma is seeking a highly motivated Senior Scientist with deep expertise in lentiviral and viral vector technologies to support nextgeneration gene and cell therapy programs. The successful candidate will play a critical role in leading a vector core team to produce viral vectors on a regular basis supporting research activities throughout the addition they will initiate and design experiments for the optimization and characterization of viral delivery platforms. They will work cross-functionally interfacing with teams in discovery analytical development and process development.

This role is ideal for a handson scientist who combines strong technical leadership with managerial and leadership skills who can drive complex projects in a fastpaced collaborative biotech environment.

Key Responsibilities

• Lead and manage a vector core team to produce lenti and retroviral vectors supporting Research teams and activities in the organization.

• Lead experimental design and execution for lentiviral and viral vectorbased gene delivery strategies supporting CART TCRT and emerging gene therapy modalities

• Exceptional record keeping and Lab information management system policy adherence

• Develop optimize and characterize viral vector production for in vivo and ex vivo lentiviral systems

• Apply deep understanding of viral biology vector engineering and gene expression control to improve efficiency safety and scalability

• Serve as a technical expert for viral delivery providing guidance to discovery translational and process development teams

• Collaborate crossfunctionally with Research teams core groups analytical development process development and regulatory partners

• Interpret complex datasets troubleshoot experimental challenges and drive datadriven decision making

• Author technical reports protocols and contribute to INDenabling documentation as needed

• Present results at internal forums and external scientific meetings

• Mentor direct reports and contribute to building best practices within the viral vector group

Basic Qualifications

• Advanced scientific degree (MD PharmD PhD) in Molecular Biology Cell Biology Virology Bioengineering or a related field with 2 years of relevant postdoctoral or industry experience
  OR

• Masters degree in Molecular Biology Cell Biology Virology Bioengineering or a related field with 6 years of relevant scientific experience
  OR

• Bachelors degree in Molecular Biology Cell Biology Virology Bioengineering or a related field with 8 years of relevant scientific experience

Preferred Qualifications

• Ph.D. in Molecular Biology Cell Biology Virology Bioengineering or a related field with 3 years of relevant postdoctoral or industry experience

• Demonstrated handson expertise in lentiviral vector design optimization production and transduction

• Strong background in viral gene delivery for cell or gene therapy applications

• Strong leadership and managerial skills

• Proven ability to work in a highly matrixed environment

• Deep knowledge of mammalian cell culture transfection/transduction methods and molecular biology techniques (e.g. ddPCR qPCR flow cytometry Western blot ELISA)

• Proven ability to independently design and execute complex experiments

• Strong written and verbal communication skills

• Experience supporting CART or engineered cell therapy programs

• Knowledge of nonlentiviral viral systems (e.g. retroviral AAV vectors)

• Experience with scaleup process development or tech transfer of viral vectors

• Experience with high throughput screening automation and use of liquid handers (Biomek TECAN etc)

• Experience with viral vector producer cell line improvement and optimization strategies.

• Track record of publications patents or successful program contributions

Key Competencies

• Scientific rigor and experimental excellence

• Crossfunctional collaboration and leadership

• Strategic thinking with attention to detail

• Ability to thrive in a fastmoving resultsdriven environment

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and kill tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:

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