Associate Scientist, Protein Engineering & Binder Discovery Support

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Job Description

We are seeking a motivated and versatile Associate Scientist to join the Protein Engineering & Binder Optimization group within Kite Research. This role is designed to support binder discovery and optimization campaigns through handson laboratory execution across protein expression screening and analytical workflows.

The Associate Scientist will execute key experimental components of binder campaigns including protein production library handling screening assays and data generation. This position is well suited for an individual who enjoys contributing across multiple stages of discovery workflows values rigor and reproducibility and thrives in a fastpaced collaborative research environment.

Key Responsibilities

Binder Discovery & Screening Support (Primary Focus)

• Execute handson experimental workflows supporting binder discovery and optimization campaigns including library handling selections screening assays and hit triage.

• Support screening and downselection efforts by generating highquality binding specificity and functional data.

• Perform routine experimental troubleshooting and communicate issues or observations to Scientists leading campaigns.

Protein Expression Purification & Analytics

• Perform highthroughput protein expression and purification to support screening characterization and downstream assays.

• Conduct routine protein analytical assays (e.g. SDSPAGE SEC ELISA concentration and quality assessments).

• Prepare protein samples for downstream applications such as SPR/BLI functional assays or cellbased screening.

Program Execution & Team Enablement

• Support multiple discovery programs in parallel by reliably executing experimental tasks that enable campaign progress.

• Work closely with Scientists to ensure experimental outputs align with screening strategies timelines and data needs.

• Assist with sample tracking data handoff and coordination with crossfunctional partners as needed.

Documentation & Experimental Rigor

• Maintain accurate timely experimental documentation using electronic lab notebooks and sampletracking/LIMS systems.

• Ensure reproducibility traceability and data integrity across all assigned experiments.

• Adhere to laboratory safety quality and bestpractice standards.

Workflow Support & Continuous Improvement

• Contribute to the robustness and scalability of discovery workflows through consistent execution and protocol adherence.

• Identify opportunities to improve throughput consistency or data quality and share observations with the team.

• Participate in protocol updates and workflow refinements as discovery platforms evolve.

Basic Qualifications

• Masters degree with 2 years of relevant scientific experience
  OR

• Bachelors degree with 4 years of relevant scientific experience

Preferred Qualifications

• Bachelors or Masters degree in Protein Science Biochemistry Molecular Biology Bioengineering or a related discipline

• Handson laboratory experience in protein expression purification screening or biochemical assays

• Strong attention to detail and demonstrated commitment to data quality and reproducibility

• Ability to manage multiple experimental workflows in parallel in a fastpaced laboratory environment

• Experience with librarybased screening or selection methods (e.g. phage yeast or related display technologies)

• Familiarity with protein characterization and binding assays (e.g. ELISA SPR/BLI SDSPAGE SEC)

• Experience working in electronic lab notebooks and sample/LIMS systems

• Prior experience supporting protein engineering or binder discovery programs

Attributes for Success

• Reliable executionoriented experimentalist who takes pride in highquality bench work

• Organized and methodical with strong sample tracking and documentation habits

• Comfortable working across multiple stages of discovery workflows

• Collaborative team member who works effectively with Scientists Principal Scientists and crossfunctional partners

• Motivated to build technical depth in binder discovery screening and protein production within a discovery research environment

This Associate Scientist role will support overlapping binder discovery screening and protein expression activities.

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and kill tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:

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