Scientist, Cell Therapy Process Development

This position within the Process Development team will involve substantial amount of hands-on cell culture work essentially human CAR-T cell generation and in vitro expansion scale up and characterize culture processes. The position will require to perform gene editing activities and human primary cells manipulation.

As a Scientist you will independently design implement analyze and document early and late-stage process development studies. You will collaborate within the team to interpret study results and contribute to technical discussions for subsequent study design and decision making. You will also contribute to tech transfer activities including batch record and SOP development real-time troubleshooting investigation and impact assessment of deviations change control management process monitoring and data analysis and risk assessments. Additionally you will author and contribute to development reports scientific publications patents and regulatory filings in different countries and regions.

Required Skills

• Experience with human primary cell culture (CAR-T cell culture experience highly preferred) and cell expansion.

• Familiar with process development for cell therapies including scale-up and cell characterization (flow cytometry PCR etc.).

• Experience engineering CAR-T cells. Hands-on experience with genome editing tools and DNA/RNA transfection approaches.

• Familiar with the fundamentals of DOE.

• Strong background in experimental design and data analysis skills are essential.

• Ability to think critically analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoning.

• Excellent teamwork and communication skills including proven technical writing skills are required. Position may require weekend work.

Desired Skills:

• Knowledge about immunology and GMP manufacturing is highly desirable.

• Experience with cell editing technologies: CRISPR/Cas9 gene editing etc.

• Experience with viral transduction techniques desirable.

• Scientific rigor in assessing own data and that of others. Utilizes forward-looking perspective to contribute to go/no go decisions.

Education/Experience:

• BS degree in Biochemical Engineering Biomedical Engineering Biotechnology or related field with 2-5 years or MS degree with a minimum of 2 years of relevant proven experience.

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The annual base salary for this position ranges from $92252.00 - $138378.00. However base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to partticipate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.