Principal Scientist – Biopharmaceutics Strategy
Job Summary
Job Title: Principal Scientist Biopharmaceutics Strategy
Location: Gothenburg Sweden
Hybrid working: 3 days onsite
At AstraZeneca we unlock the power of what science can do. Delivering our ambitious pipeline requires not only deep expertise but senior scientific leaders who can set direction manage risk and influence outcomes across a sophisticated global organisation!
Join us as a Principal Scientist and become the driving force behind groundbreaking Biopharmaceutics innovation on a global scale.In this pivotal leadership role within our Global Product Development team youll shape the scientific vision and strategic direction of our Biopharmaceutics group directly influencing how life-changing medicines reach patients worldwide.
This is your chance to define a transformative impactacross our entire portfoliofrom steering critical project decisions that determine the future of our pipeline to building world-class capabilities that set new industry standards. Youll not only lead pioneering scientific initiatives but also elevate AstraZenecas external scientific reputation positioning us at the forefront of biopharmaceutics excellence.
Ready to lead the science that changes lives
Global Product Development (GPD) part of PT&D is accountable for transforming discovery science into robust approvable and commercially viable medicines across oral parenteral and pulmonary delivery routes. The Biopharmaceutics group is a critical decisionenabling capability in this environmentsupporting formulation design product development bioequivalence strategies regulatory interactions lifecycle management and digital transformation objectives across PT&D and Operations with a focus on maximising robust product performance in our patients.
The Principal Scientist operates at enterprise level shaping how Biopharmaceutics insight is generated communicated and applied across projects sites and modalities.
Role Overview
As a Principal Scientist you will be recognised internally and externally as a scientific authority in Biopharmaceutics with strong digital competence and a proven track record of impactful science based influencing.
Accountable for setting scientific direction and standards for the discipline influencing highimpact development and portfolio decisions and building sustainable capability and strategic leadership across GPD and PT&D.
Offering a global remit working across therapeutic areas development phases and sites this role is based out of our Gothenburg (Sweden) location.
Key Accountabilities
Enterprise Scientific Leadership
Define and evolve the Biopharmaceutics scientific strategy for GPD in alignment with PT&D and enterprise priorities.
Provide authoritative scientific judgement on complex highrisk development questions spanning multiple products or platforms.
Lead governance discussions decision forums and crossfunctional risk assessments.
Portfolio & CrossProduct Impact
Supervise and guide the application of PBBM modelling advanced in-vitro and regulatory approaches across the portfolio ensuring consistency quality and credibility
Identify crossproduct opportunities risks and capability gaps and drive aligned solutions.
Influence bridging strategies control strategies and lifecycle plans with downstream commercial and regulatory impact.
Capability Network & Talent Leadership
Lead disciplinelevel initiatives networks or communities of practice within GPD/PT&D.
Coach and mentor technical experts across career levels strengthening scientific depth and succession.
Collaborate with line leaders to grow the groups capability and talent ensuring the challenges of the future portfolio are fully met and our people flourish.
Establish and maintain standards procedures and knowledge frameworks for Biopharmaceutics science.
External Scientific Leadership
Act as an external ambassador for AstraZeneca in Biopharmaceutics.
Build and sustain strategic external partnerships (academia industry consortia vendors).
Drive innovation publications and intellectual property that enhance AstraZenecas scientific reputation.
Skills Experience & Leadership Profile
- PhD (or equivalent experience) in Biopharmaceutics Pharmaceutical Sciences or a closely related field.
- Demonstrated track record of applying Biopharmaceutics science (e.g. risk acceptance strategy and regulatory positioning) to shape development plans and influence outcomes across multiple drug products through authoritative scientific judgement.
- Proven effectiveness at shaping development plan decisions e.g. progression risk acceptance Biopharmaceutics strategy regulatory positioning through authoritative scientific judgement.
- Skilled in digital Biopharmaceutics with experience applying shaping or critically evaluating modelling simulation and/or AI enabled approaches to inform scientific judgement and development strategy.
- Clear evidence of leading a scientific discipline through influencing establishing best practice building capability beyond own team and developing other senior experts.
- Collaborative leadership capability working effectively across functions sites modalities and seniority levels.
- Established external scientific credibility evidenced by recognised contributions through publications invited speaking strategic collaborations consortia leadership IP or regulatoryfacing engagement.
This role is a senior scientific leadership position with enterpriselevel scope and accountability intended for scientists who have demonstrated impact beyond individual projects operating at portfolio platform or discipline level.
What makes this role unique
This is a rare opportunity to take on a global scientific leadership roleshaping how biopharmaceutics insight influences medicines that reach patients worldwide.
At AstraZeneca you will work in an environment that values scientific authority critical thinking and inclusive leadership. We offer flexible ways of working and demonstrate dedication to development and innovation.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
If this role matches your experience and ambitions apply now to help shape how Biopharmaceutics drives the next generation of medicines!
**Please note: we operate a rolling recruitment process and may close this vacancy early if a strong candidate is identified. Early applications are strongly encouraged.
Competitive salary and benefits package on offer.
The successful candidate will have access to a flexible employee benefits fund including holiday purchase and flexible time off pension contributions Share Save Plans a performance recognition scheme and a competitive generous remuneration package
Date Posted
27-Apr-2026Closing Date
15-May-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Staff IC
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more