Staff Bioinformatics Engineer

ABOUT SINGULAR GENOMICS

We foster a culture of creativity and technical excellence both catalysts for innovation. We celebrate diversity emphasize collaboration and as we rapidly mature we are constantly looking at ways we can do better for our people.

POSITION SUMMARY:

We are hiring a Staff Bioinformatics Platform Engineer to build and own the internal applications and execution platform that run our bioinformatics workflows. You will lead architecture and implementation of tools that support Nextflowpipeline execution on AWS Batch integrate with operational systemsincludingSlackJiraandHubSpot and automate data flow into our data lake.This is a small-team role combining technical leadership with hands-on delivery.This position can be remote or hybrid/ remotetravel to the headquartersin San Diego CAwill beat least quarterly.

• Own end-to-endNextflowworkflow execution: run launch configuration tracking retries/failures metadata capture and auditability on AWS Batch.
• Build internal web apps and services that enable operational workflows (e.g. custom panel design QC/reporting runmonitoring).
• Integrate pipeline events and outcomes with Slack Jira and HubSpot to support scalable operations.
• Lead hands-on data analysis tovalidatepipeline outputs investigate anomalies/QC trends and translate findings into improvements to workflows tooling and operational processes.
• Implement automated pipelines for key QC processes (including reagent QC) and land outputs/metadata into Snowflake.
• Define and improve processes around tools: runbooks quality gates observability and operational best practices.

• Senior-level experience building andoperatingscientific/bioinformatics applications in production.
• Demonstrated experience developing running and supportingNextflowpipelines in production.
• Strong Python engineering skills and experience building backend services/APIs.
• Experience building web applications with Reactor equivalent modern front-end framework.
• Experienced in HPC-computing and Linux-based operating systems.
• Experience deploying/operating workflows on AWS ideally including AWS Batch.
• Experience integrating systems via APIs/webhooks (SlackJiraHubSpot or similar).
• Ability to drive architecture decisions align stakeholders and implement pragmatic processes in a small team.
• Ability to provide interpretable and actionable results from bioinformatic analyses.

PREFERRED QUALIFICATIONS

• Experience in NGS sequencing environments with exposure to single-cell and/or spatial workflows.
• Experience with Snowflake and building automated data pipelines.
• MLOpsexperience: batch inference/training pipelines model packaging/registry monitoring.

The estimated base salary range for this role based in the United States of America is: $129.100 - $163000. Additionally this role is eligible for one of our variable cash programs (bonus or commission) and may receive equity as part of the compensation package. Compensation decisions are dependent on several factors including but not limited to an individuals qualifications location where the role is to be performed internal equity and alignment with market data. Should the level of the role change during the hiring process the applicable salary range may be updated accordingly.

Singular Genomics is committed to working with and providing reasonable accommodations to job applicants with physical or mental disabilities. Applicants with a disability who require a reasonable accommodation for any part of the application or hiring process can provide their name and contact information to our Accommodations team at . Your request will be responded to as soon as possible.