Medical Director, Early Development & Experimental Medicine (Neuroscience)

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

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Johnson & Johnson is recruiting for Medical Director Clinical Leader- Neuroscience Early Development & Experimental Medicine to be located in Raritan NJ Titusville NJ or Spring House PA. Remote work options may be considered on a case-by-case basis and if approved by the Company.

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Neuroscience team tackles the worlds toughest brain health challenges including multiple sclerosis Alzheimers disease Parkinsons disease myasthenia gravis epilepsy major depressive disorder bipolar disorder schizophrenia and autism. This patient-focused team helps address some of the most complex diseases of our time.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at Clinical Leader for Neuroscience Early Development & Experimental Medicine will serve as the clinical lead for one or multiple earlystage programs in Neuroscience. This role will be accountable for shaping the clinical strategy designing and overseeing earlyphase clinical studies and driving programs from firstinhuman through ProofofConcept.

The role requires deep scientific and clinical expertise in neuroscience strong leadership in crossfunctional drug development and the ability to operate in an innovationfocused matrix environment. The Medical Director Clinical leader will partner closely with discovery precision measures (e.g. biomarkers diagnostics) clinical pharmacology biostatistics regulatory and external academic collaborators to advance transformative therapies for patients.

Key Responsibilities

• Develop and lead clinical development strategies from IND/CTA through Phase I and Phase IIa ProofofConcept/Proof-of-Mechanism.

• Integrate translational hypotheses biomarker strategies precision measures (for patient selection pharmacodynamic measures) and patientcentric approaches into clinical plans.

• Ensure scientific rigor clinical feasibility and regulatory alignment in all development strategies.

• Lead the design of innovative and lean signal seeking early-phase clinical trials including adaptive and biomarkerenriched designs.

• Provide clinical oversight for study execution including protocol development medical monitoring and data interpretation.

• Leads cross-functional clinical study teams and work closely with biomarker PK/PD biostatistics and operations teams to ensure highquality clinical execution.

• Be a core member of the early development compound team for specific assets. Guide decisionmaking at project milestones and participate in governance reviews.

• Engage with regulatory affairs to inform early interactions with FDA EMA and other agencies.

• Establish and maintain relationships with global key opinion leaders academic partners and clinical investigators.

• Represent the company at scientific meetings advisory boards and consortiums in neuroscience and neurodegeneration.

• Contributes to in-licensing evaluations and due-diligence activities.

• Provide scientific and strategic leadership to clinical scientists and clinical development team members.

• Promote a culture of scientific excellence patient focus and collaborative innovation.

Education & Experience:

• MD MD/PhD or equivalent clinical degree required; board certification in Neurology or Psychiatry strongly preferred.

• Minimum 5 years of clinical research experience in the biopharmaceutical industry academia or equivalent setting.

• Demonstrated experience leading earlyphase clinical trials; experience in Parkinsons disease and Alzheimers Disease is highly desirable.

• Proven track record of advancing programs through early development milestones.

• Deep understanding of neurodegenerative diseases including Alzheimers and Parkinsons biology clinical endpoints and emerging modalities.

• Strong knowledge of translational neuroscience biomarkers and experimental medicine approaches.

• Experience with innovative trial designs digital health tools or fluid/imaging biomarkers is a plus.

• Strategic thinker with the ability to influence and drive crossfunctional teams.

• Outstanding communication and presentation skills with the ability to engage senior leadership and ensures alignment between various teams and stakeholders.

• Demonstrated ability to work in an agile innovationdriven environment.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please contact us via or contact AskGS to be directed to your accommodation resource.

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Director