Associate DirectorDirector, Commercial Project Management

Associate Director/Director Commercial Project Management

Skyhawk Therapeutics is seeking a highly motivated and experienced Associate Director Commercial Project Management to lead cross-functional planning and execution for the launch of SKY-0515 a potential first-in-class disease-modifying therapy for Huntingtons disease. This is a rare opportunity to play a central high-visibility role in shaping and delivering one of the most anticipated launches in rare neurological disease.

Reporting to senior commercial leadership the Associate Director will serve as the central coordinator and integrator across clinical regulatory medical affairs market access and commercial teams driving launch readiness with rigor urgency and strategic clarity.

Responsibilities (including but not limited to):

Launch Planning & Execution

• Develop own and manage the integrated launch plan including timelines milestones workstream interdependencies and critical path to regulatory approval and commercialization
• Define and continuously refine the critical path to NDA/regulatory submission and commercial launch across all functional workstreams.
• Lead launch readiness reviews and go/no-go decision frameworks ensuring senior leadership has timely accurate and actionable information.
• Develop and maintain executive- and board-level launch dashboards and status reporting that distill complexity into clear progress narratives.
• Proactively identify risks to launch timelines and readiness; develop contingency plans and adapt as new data regulatory feedback or business priorities emerge.

Cross-Functional Coordination

• Ensure strategic and operational alignment across regulatory clinical CMC medical affairs market access commercial and finance workstreams.
• Lead and facilitate launch team working groups; maintain accountability for key decisions next steps and action items.
• Partner with Medical Affairs on publication planning congress strategy and scientific communication platform execution.
• Coordinate HCP field force readiness activities including training timelines materials development and deployment planning.
• Support payer and market access workstream planning including reimbursement strategy milestones and patient services infrastructure.
• Manage external vendors consultants and agency partners engaged in commercial launch readiness.

Project Management Infrastructure

• Build maintain and continuously improve core project management tools and systems (e.g. Smartsheet Asana).
• Oversee launch budget tracking and resource planning in close coordination with Finance.
• Establish best-in-class PM processes appropriate for a fast-moving resource-efficient small company environment.

Education / Skills / Experience Required:

Required

• Bachelors degree required; advanced degree (MBA MS or equivalent) strongly preferred.
• 810 years of experience in the biotech or pharmaceutical industry with demonstrated progression in responsibility.
• Meaningful experience in late-stage development and/or commercial launch including parallel NDA/BLA submission and launch preparation.
• Proven track record leading complex cross-functional projects in matrixed environments with multiple senior stakeholders.
• Exceptional project management and organizational skills able to manage multiple workstreams simultaneously without losing detail or momentum.
• Strong executive communication and presentation skills ability to synthesize complexity and present clearly to senior leadership and board audiences
• Comfort and effectiveness operating in fast-paced evolving small-company settings where ambiguity is the norm and ownership is expected.

Preferred

• Experience in Huntingtons disease neurology CNS or rare/specialty disease strongly preferred.
• Familiarity with FDA rare disease regulatory pathways including Breakthrough Therapy Designation Orphan Drug Designation and accelerated approval mechanisms.
• Experience with international regulatory submissions and ex-US launch coordination (e.g. EMA TGA).
• Proficiency across project management platforms (Smartsheet Asana Veeva or equivalent).
• Prior experience at a company navigating first commercial launch.

About Skyhawk

Skyhawk is committed to discovering developing and commercializing small molecule therapeutics that modify RNA expression. We use our novel SkySTAR platform (Skyhawk Small molecule Therapeutics for Alternative splicing of RNA) to develop drug candidates directed toward targets for some of the worlds most intractable diseases including neurological conditions cancer and traditionally undruggable targets.