Senior Principal ScientistAssociate Director PK Sciences (DUAL LEVEL POSTING)

Job Description Summary

Job Description

Key Responsibilities:
Independently represent the PK Sciences function in cross-functional project teams interactions with stakeholders within the organization and interactions with regulatory agencies as appropriate
Lead a PK Science Subteam with interdisciplinary representation of the major functions from within PK Science and beyond
Ensures implementation of project strategies and monitors timelines objectives and budgets for assigned projects
Present projects at various institutional review and approval boards
Proactively contributes to developing drug candidates across Research Development and Commercial continuum providing expert pharmacokinetic / drug metabolism and clinical pharmacology input
Develop and execute clinical pharmacology strategies including input into nonclinical and clinical study design and analyzing PK and PK/PD data to support compound development from discovery through late development
Provide PK dosage PK/PD and M&S component of study protocols reports project summaries and development plans and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections/radiation dosimetry of IND/IMPDs and NDA/BLAs as well as prepare appropriate responses to global Health Authority questions
Use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design preclinical and clinical data automation authoring regulatory documents and the use of predictive models
Is a mentor to or manages junior associates in the organization

This role reports to Therapeutic Area Head in PK Sciences within Translational Medicine (TM) in Biomedical Research. PKS is a global organization situated within Translational Medicine (TM) the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients by building on research advances to develop new therapies bridging drug discovery and clinical application. PK Science is an enterprise-wide organization working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics metabolism and clinical pharmacology.

Essential Requirements:
Ph.D. / Pharm.D. with relevant experience
Preferred candidates will have a minimum of 5 yrs at the Senior Principal Scientist Level and 8 years at the Associate Director level) in clinical pharmacology drug metabolism and pharmacokinetics or a related background in an industry setting.
Extensive and in-depth knowledge of pharmacokinetics including drug metabolism and PK/PD evaluation experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.
Demonstrated success in working in a cross-functional matrixed project-team environment.
An influential Team player and talented negotiator with strong oral and written communication skills.
Proven record of mentorship and/or people management

Desirable Requirements:
Hands-on project experience with Artificial intelligence (AI) / Machine Learning (ML) approaches is a plus

Leadership / Novartis Behaviors in Action
Delivers results through disciplined execution continuous improvement and a strong focus on value and outcomes.
Demonstrates an enterprise mindset and strong ownership by prioritizing resources and decisions for maximum Novartis and patient impact.
Role models Novartis leadership behaviors through visible actions continuous self reflection and openness to feedback
Builds trust through transparent communication clear accountability and consistent delivery against commitments.
Empowers others to innovate and improve while maintaining high scientific ethical and operational standards.

AI fluency:
Brings strong AI and digital fluency using enterprise tools to enhance insight generation decision making and team productivity.
Accountable for the ethical transparent and compliant use of AI in line with Novartis AI governance and data protection standards.

External eminence:
Acts as an external thought leader advancing Novartis reputation in translational science and innovation.

Operational excellence:
Drives operational excellence through disciplined execution continuous improvement and effective use of resources to maximize PKS and enterprise value.
Acts as a responsible steward of people data and digital capabilities leveraging AI and automation to improve efficiency quality and decision speed.

This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills experience & capabilities required to perform the role at the level the role has been offered.

The salary for this position is expected to range between:

Senior Principal Scientist: $138600 and $257400 per year.
Associate Director: $145600 and $270400 per year.

The final salary offered is determined based on factors like but not limited to relevant skills and experience and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and depending on the level of the role eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health life and disability benefits a 401(k) with company contribution and match and a variety of other addition employees are eligible for a generous time off package including vacation personal days holidays and other leaves. To learn more about the culture rewards and benefits we offer our people click here.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion sex national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or to perform the essential functions of a position please send an e-mail to or call 1 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

Skills Desired