Senior Manager, Business Analysis and Project Management

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The companys R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The companys RAS(ON) inhibitors daraxonrasib (RMC-6236) a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291) a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805) a RAS(ON) G12D-selective inhibitor; and RMC-5127 a RAS(ON) G12V-selective inhibitor are currently in clinical development. As a new member of the Revolution Medicines team you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Manager Business Analysis & Project Management is a strategic leadership role within the Information Sciences organization responsible for driving enterprise technology initiatives that support pharmaceutical research development manufacturing quality and commercial operations. This role requires creation of business and Sciences requirements leading to delivery of complex cross-functional projects while maintaining compliance with regulatory and validation requirements.

The role partners closely with business and IS leadership to translate business strategies into scalable compliant technology solutions while ensuring projects are delivered on time within scope and within budget.

Key Responsibilities:

Strategic Leadership & Governance

• Develop and execute the Business Analysis and Project Management strategy aligned with enterprise IS and business objectives.

• Establish and enforce standardized methodologies templates tools and best practices (Agile Waterfall Hybrid).

• Provide portfolio-level oversight prioritization and delivery governance for IS initiatives.

• Serve as a trusted advisor to senior business and IT stakeholders.

Business Analysis & Stakeholder Partnership

• Lead business analysis activities including facilitating workshops to elicit document and validate complex business and functional requirements.

• Partner with stakeholders across R&D Clinical Regulatory Quality Manufacturing Supply Chain and Commercial functions to document and map current and future-state business processes.

• Identify process gaps redundancies and optimization opportunities including integrations.

• Ensure integration points and downstream impacts are identified and addressed.

• Analyze data flows across Sciences and functions.

• Translate business needs into clear structured system requirements.

• Ensure solutions align with end-to-end business operations.

• Ensure traceability of requirements through design development testing and deployment.

• Support user acceptance testing and validation.

• Drive data-driven decision-making and continuous process improvement.

Project & Program Management

• Lead planning and execution of multiple concurrent projects and programs of varying size and complexity.

• Manage project scope schedule budget risks issues dependencies and change control.

• Ensure alignment of project outcomes with business value realization.

• Oversee vendor performance contracts and delivery outcomes.

Compliance Validation & Risk Management

• Ensure all IS projects comply with pharmaceutical regulatory requirements (e.g. GxP FDA SOX GDPR as applicable).

• Partner with Quality Assurance and the Computer System Validation team to support system validation audits and inspections.

• Identify assess and mitigate operational technical and compliance risks.

Required Skills Experience and Education:

• Bachelors degree in Information Sciences Computer Science Business Administration or related field (Masters degree preferred).

• 10 years of experience in Business Analysis Project Management or IS delivery roles.

• Experience working in a pharmaceutical biotechnology or life sciences environment.

• Proven success delivering complex cross-functional enterprise Science.

• Strong understanding of SDLC Agile Waterfall and hybrid delivery models.

• Experience with R&D Commercial & MedAffairs and G&A systems.

• Expertise in requirements management business process modeling and solution design.

• Strong financial risk and vendor management skill.

• Working knowledge of GxP system validation and regulated system environments.

• Experience supporting audits and regulatory inspections.

Preferred Skills:

• PMP PgMP PMO-CP.

• CBAP CCBA.

• Agile certifications (SAFe Scrum Master Product Owner).

• Lean Six Sigma Certifications.

#LI-Hybrid #LI-YG1

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