Senior Global Medical Affairs Leader, Obesity

AstraZeneca is advancing a tailored approach to Obesity and Weight Management uniting science medical and commercial excellence to deliver durable outcomes reduce cardiometabolic risk and protect organs. Our pipeline is moving with purpose and includes next generation oral and injectable therapies that prioritises tolerabilitydurabilityand quality of life.Are you ready to be at the forefront of medical innovation As theSeniorGlobal Medical Affairs Leaderfor ObesityandRelated Complicationsyoullplay a pivotal role in shaping the future ofobesity care. This is your chance to use yourexpertiseto make a real impact on patients lives. Join us in our mission to transform the patient journey from prevention to diagnosis and beyond.

Accountabilities

In this dynamic roleyoullbe responsible forproviding medical leadership across the entire product lifecycle.Youlladvise on Research & Development investment decisions lead pre-launch scientific efforts and accelerate evidence-based healthcare changes in the real world. Your networking and influencing skills will be key as youfacilitatecross-functional collaboration and drive innovation. Are you ready to take on this challenge

Role Summary:

Reportingto the MedicalHeadofWeightManagement the Senior GMAL is ahighlyexperiencedMedical Affairsleaderwithproven vision andimpact.Thisindividualdevelopsandleadsboldmedicalstrategieswithintheobesityandcardiorenal-metabolicoutcomestherapyarea(specificallyMASHheartfailureand CKD)expertlyguidingcross-functionaland cross-regional teams todeliverandexceedambitiousgoals. The SeniorGMALsinfluenceisenterprise-wideshapingglobalmedicalagendasthroughGlobal Medical Team Global Product Team andDiseaseArea Teamleadership anddeeppartnershipwithMedical and Commercialfunctionsin marketsand regionsworldwide.

Thisroledemandsaleaderwhochampions innovativedisruptivethinkingidentifiesandshapesbreakthroughopportunitiesreimaginesmarketdynamics andaccelerateshigh-impactevidencegeneration andmedicalchangeinitiatives. The Senior GMALnavigatesand transformshealthsystems leverages digital andadvancedanalytics drivesstakeholderengagement andensuresAstraZenecasscienceleadsexternallyandinternallythroughworld-classmedicalevidenceandstrategicpartnerships.

Expectations of a Senior GMAL include:

• Strategy& Transformation:The Senior GMAL designs andleadsthe implementationofproductanddiseaseareastrategies aswellasambitiouspracticechangeinitiatives at a globallevel.Thisrequiresadeepunderstandingofhealthcare systempathwaysregulatorylandscapesmarket access andcompetitivedynamics. The Senior GMALconsistentlydelivers innovativedisruptivesolutions toshapemarketschallengesstatusquothinking andusesdigitalproficiencytoidentifydata-drivenopportunitiespreparingforlaunchandlifecyclemanagement.

• MedicalEvidenceLeadership:SeniorGMALsowntheevidencegenerationstrategydemonstratingadvancedexperienceinclinicalresearchinterventionaltrials(Phases24) and real-worldevidence(RWE) programs.Theyshapeand drivegroundbreakingclinicaltrialsregistries and RWE studiesalignedwithbrand access andpractice-changingobjectives.Theyguide theoptimisationcommunication andstrategicroll-outofdataacrossscientificplatformsensuringAstraZeneca deliversdifferentiatedevidencethatsupports theneedsofregulatorypayer and healthcareproviders. Clinical research patientoutcomesexpertise anddeepunderstandingoftreatmentprotocolsunderpintheirabilitytoaddressevolvingevidencerequirements.

• AdvancedScientific& DigitalEngagement:The Senior GMALblendsscientificexpertisewithstrong digitalacumen.Theyleveragedigitalhealthtoolsadvancedanalytics and dataplatformsto transformevidencecommunicationpersonalizestakeholderengagement andenhancepatientoutcomes.Theyarethe voiceofmedicalcraftingcompellingnarrativesdrivingdigital disseminationofevidence andensuringaccurateimpactful andcompliantscientificcommunications.

• GuidingandInfluencingStakeholders:Withsignificantexpertiseininternalandexternalengagement the Senior GMALbuildsandsustainspowerfulrelationshipsacrossthe healthcareecosystemincludingglobal and regionalKOLsprofessionalsocieties regulatorspayers patientorganizations digitalinnovators andhealthsystems.Theircredibilityandinfluenceenablethemtomobilizesupport formedicalstrategyevidencegeneration and healthcarechangeinitiatives.Theymentor andguide cross-functionalteamschampioningscientificleadershipandstrategiccollaboration.

• RegulatoryInsight&Compliance:The Senior GMALpossesseskeenregulatoryunderstandingandensuresclinicaltrial andevidencegenerationinitiativesaredesignedforbothscientificandregulatorysuccess.Theyanticipateevolvingregulatoryandpayerrequirementsforevidenceensuringhighqualitycompliantdata generation andcommunicationateverystage.

Essential for the role:

• Doctoral-level degree (MD PhD PharmD)

• Masters degree with at least5 yearsof experience in the pharmaceutical industry (Medical Marketing R&D Market Access) or extensive experience within a health system (clinical pharmacy pathway design etc.).

• Demonstrated leadership in complex global healthcare environments including leading franchise/TA business in key markets driving brand performance and managing large diverse teams.

• Significantexpertiseand strategic insight into healthcare system pathways regulatory landscapes market-shaping and external stakeholder engagement.

• Strongtrack recordof internal and external network building collaboration across geographies and matrix teams and effective mentoring of junior colleagues or peers.

• Digitalproficiencyleveragingdigital health tools and data platforms to advance evidence generation and communication.

• Deep understanding of patient care pathways evolving treatment protocols scientific literature and contemporary approaches to healthcare transformation.

• Proven ability to guide influence and align diverse stakeholdersincluding thought leaders regulatory bodies patient groups and payer organisations.

Desirablefor the role:

• Clinicalexperience inobesity PCPheartfailureand/or CKD

• Experience with the USA health care system

• Recognisedexpertisein the relevant or related therapeutic area oftenevidencedby a history of clinical practice research leadership or significant external engagement.

• Advanced experience designing leading and interpreting clinical research programs including pivotal clinical trials (Ph2Ph4) practice-changing RWE studies and implementation of innovative evidence generation approaches.

• Broad experience beyond Medical Affairs; for example prior roles in Marketing R&D or Market Access.

• Long-standing relationships with global KOLs societies regulators digital health partners and innovative healthcareorganisations.

• Track recordof launching new products or indications in multiple diverse markets (e.g. US China EU) and successfully developing and executing global medical strategies.

• Location;Boston Massachusetts USA(relocation support provided)

Total Rewards:

The annual base pay (or hourly rate of compensation) for this position ranges from $243586 to $365379 Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.

AstraZenecais an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment assessment and selection process and may be requested by emailing.