Senior Scientist, Analytical Research and Development Onsite

Job Description

The Materials and Biophysical Characterization group in Analytical Research and Development is seeking a highly self-motivated and innovative scientist with deep knowledge and problem-solving skills in biotherapeutics characterization. The Materials and Biophysical Characterization team is responsible for building the mechanistic understanding of the interplay between formulation composition stability device and process to ensure robustness and quality of drug substances and drug products in the biotherapeutics pipeline.

As a Senior Scientist you will be contributing to projects in a diverse biotherapeutics pipeline by developing and implementing biophysical and particle characterization assays and collaborating with process formulation and device functions as part of the CMC development team. You are expected to use your scientific expertise to find creative solutions to challenging problems which require deep analytical insight and critical thinking. Additional responsibilities include authoring technical reports and regulatory documents presenting technical data and project management. You will have the opportunity to conduct independent research publish research findings present at scientific conferences and engage with various external scientific societies/organizations. This is an excellent growth and learning opportunity to work in an exciting collaborative environment with a wide array of scientists from different divisions and make significant contributions towards our life-saving medicines.

Education Minimum Requirement:

• Ph.D. in Biophysics Biochemistry Chemistry Chemical Engineering Biomedical Engineering Pharmaceutical Sciences or related discipline

OR

• M.S. in Biophysics Biochemistry Chemistry Chemical Engineering Biomedical Engineering Pharmaceutical Sciences or related discipline with a minimum 4 years of relevant industry experience.

Required Experience and Skills:

• Experience in the analysis of biologics protein/peptide stability protein-protein interactions

• Experience with subvisible and submicron particle characterization tools (e.g. flow imaging microscopy backgrounded membrane imaging (BMI) flow cytometry dynamic light scattering (DLS))

• Hands-on experience in biophysical characterization of proteins and peptides (e.g. Circular Dichroism (CD) Infrared Spectroscopy (IR) Differential Scanning Calorimetry (DSC) Analytical Ultracentrifugation (AUC))

• Understanding of protein aggregation mechanisms and link between analytical methodologies for analysis

• Ability to deliver complex objectives under aggressive timelines in a rapidly changing environment

• Demonstrated ability for taking initiative creativity and innovative problem solving.

• A strong team player with excellent oral and written communication skills; ability to work both independently and cross-functionally

Desired Experience and Skills:

• Experience with characterization of lyophilized protein formulations

• Experience with Small Angle Xray Scattering

• Experience with molecular modeling.

• Experience with biological formulation development and analytical method development.

• Experience with various biologics modalities including peptides mAbs ADC fusion proteins

Required Skills:

Preferred Skills:

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Effective September 5 2023 employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week Monday - Thursday although the specific days may vary by site or organization with Friday designated as a remote-working day unless business critical tasks require an on-site Hybrid work model does not apply to and daily in-person attendance is required for field-based positions; facility-based manufacturing-based or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

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