Principal Scientist, Inflammation Research

At Gilead were creating a healthier world for all people. For more than 35 years weve tackled diseases such as HIV viral hepatitis COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the worlds biggest health challenges and our mission requires collaboration determination and a relentless drive to make a difference.

Every member of Gileads team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions and were looking for the next wave of passionate and ambitious people ready to make a direct impact.

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Job Description

We are seeking an experienced immunologist to lead a talented team of scientists supporting the development of novel biologic therapies in autoimmune disease. The successful candidate will conduct and oversee in vitro and in vivo pharmacology studies supporting both lead and early discovery programs in immunology and will require rigour in delivering data packages for progression to development. They will collaborate across functions to pursue creative science in the service of discovering novel medicines that impact patients lives.

Additional Key Responsibilities

Leadership

• Mentor a lab-based scientific team advancing their projects and careers.

• Serve as a scientific and technical thought leader throughout the Research organization.

• Collaborate across functions to guide interdisciplinary projects with experts in immunology protein engineering chemistry translational medicine biomarkers and clinical development. Identify project risks and mitigate effectively while communicating with project teams and other leaders.

Innovation and Scientific Acumen

• Proactively ideate to accelerate early-stage discovery activities enhance understanding of disease mechanisms and develop new technologies and novel targeting modalities.

• Design and implement rigorous in vitro assays based on thorough literature review to support the development of therapeutic antibodies in autoimmune disease

• Work with internal teams and contract research organisations to plan and co-ordinate in vivo models for DMPK and efficacy

• Develop endpoint analysis including ex vivo profiling to better understand drug mechanism of action

• Develop expertise in relevant scientific fields and the external landscape including the scientific literature conference proceedings and competitive an in-house expert propose creative and rigorous research to discover validate and understand targets.

• Think critically and creatively emphasizing nimble decision making that balances risk-taking with thoughtful experimentation within the strategic/competitive context to fuel a differentiated pre-clinical pipeline.

• Contribute expertise to multi-disciplinary due diligence teams to evaluate and recommend partnerships and acquisitions.

• Contribute to research reports INDs and patent filings.

• Establish an external presence through peer-reviewed publications conference presentations and external collaborations.

Knowledge Experience and Skills

• PhD and 5 years of experience (immunology drug discovery target identification and technology development) with industry experience highly preferred.

• Strong track record of impact in scientific field including first- or senior-author publications in peer-reviewed journals and conference presentations.

• Strong knowledge base in basic immunology and pathogenesis of autoimmune disease

• Broad technical skillset of cutting-edge methods and models of immunology in vitro and in vivo

• Demonstrated success in leading research teams to productive creative data-driven decisions.

• Team-centric mindset with proven managerial excellence and ability to motivate skilled team members from diverse backgrounds.

• Excellent communication and interpersonal skills.

Equal Employment Opportunity (EEO)

It is the policy of Gilead Sciences Inc. and its subsidiaries and affiliates (collectively Gilead or the Company) to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law all employment actions relating to issues such as compensation benefits transfers layoffs returns from layoffs company-sponsored training education assistance social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds which may include an individuals gender race color national origin ancestry religion creed physical or mental disability marital status sexual orientation medical condition veteran status and age unless such protection is prohibited by federal state municipal provincial local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.

For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.