Director, US Forecasting & Analytics– Vaccines & Immune Therapies
Wilmington, DE - USA
Job Summary
Director US Forecasting & Analytics Vaccines & Immune Therapies (V&I)
Wilmington DE
Global Insights Analytics & Forecasting BBU
Hybrid Work- on average 3 days a week from office
The Director US Forecasting & Analytics Vaccines & Immune Therapies is a senior commercial insights leader responsible for US demand forecasting and analytics across the V&I portfolio. The role is predominantly forecast-focused serving as the US forecasting lead and strategic thought partner to Marketing Finance Market Access and US teams. The role also includes people leadership vendor management and forecasting-adjacent analytics leadership to ensure the effective deployment of analytical resources and continuous evolution of forecasting and insight capabilities within V&I. Time allocation may vary by business cycle and portfolio priorities. This position plays a critical role in shaping commercial expectations risk and opportunity framing and executive decision-making for in-market and late-stage pipeline vaccines and immune therapies.
What youll do
US Forecasting Leadership (Core Accountability)
Lead US short-term and long-term demand forecasts (TRx NBRx volume patients revenue) for V&I assets using robust patient-based and market-based models
Own forecast methodology assumptions and governance ensuring objectivity transparency and consistency with enterprise standards
Integrate primary market research epidemiology competitive intelligence access dynamics and real-world data into forecast models
Proactively identify and quantify key risks and opportunities through scenario and sensitivity analyses
Partner closely with Finance Market Access & Pricing Marketing Sales Medical and Global Forecasting to ensure alignment on assumptions and implications
Support business planning governance reviews and opportunity assessments with clear executive-ready narratives
Serve as a trusted advisor to senior marketing and finance leadership clearly articulating forecast drivers and changes
Analytics & Resource Leadership (Enablement)
Provide leadership over forecasting-adjacent analytics ensuring advanced analytics and insights are embedded into forecasting and business planning
Manage and prioritize internal analysts contractors and external vendors supporting forecasting and analytics deliverables
Partner with data analytics resources Global IA&F and GIBEX capability teams to deploy new tools data sources and modeling approaches
Champion and identify new ways to embed AI and advanced automation into the practice of data analytics and forecasting to drive efficiency scalability and decision quality
Champion continuous improvement in forecasting processes AI-enabled modeling and automation
Contribute to the development and sharing of best practices across the V&I forecasting community
Essential for the role
Bachelors degree in a quantitative scientific or business-related field required (e.g. Statistics Economics Mathematics Engineering Computer/Data Science).
8 years experience in US pharmaceutical commercial forecasting including in-market and late-stage pipeline assets
Hands-on model ownership experience (build refresh and performance tracking) across short- and long-term horizons
Expertise in scenario-based forecasting sensitivity analysis and driver-based narratives to support senior decision-making
Strong capability integrating multiple data types (e.g. IQVIA claims epidemiology RWD/RWE primary research) into coherent decision-grade forecasts
Working knowledge of advanced analytics/ML approaches (e.g. time series causal inference ensembles) and where they add value vs. traditional methods
Fluency in modern analytics tooling and automation (e.g. Python/R/SQL BI/visualization) with ability to partner effectively with data engineering and analytics teams
Demonstrated forecast governance and model risk discipline (traceable assumptions documentation and clear explanations)
Strong understanding of US market access and payer dynamics and how they impact demand (coverage contracting channel policy)
Exceptional communication: translates complex analysis into clear executive-ready insights options and recommendations
Strong commercial competence across key demand levers (positioning adoption competitive dynamics lifecycle events)
Desirable for the role
Advanced degree preferred (e.g. MBA MS PhD in Statistics Economics Decision Sciences Data Science or related discipline).
Vaccines and/or Rare Disease experience including familiarity with immunization dynamics patient-based forecasting and lifecycle management in preventive or immune-mediated therapies
Change leadership: builds adoption for new tools processes and ways of working across cross-functional stakeholders
Product mindset for forecasting: defines user needs success metrics and a roadmap for portfolio forecasting capabilities
Model lifecycle practices (e.g. reproducibility versioning monitoring/drift awareness); familiarity with MLOps concepts
Office Working Requirements
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
#LI-Hybrid
Date Posted
10-Apr-2026Closing Date
23-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Director
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more