Immunoassay Development Scientist Analyte Detection

We are seeking for hands-on immunoassay developers for a new Analyte Detection Business Unit. If you have designed assays from scratch selected and screened reagent pairs and solved real development problems across ELISA MSD TR-FRET AlphaLISA or related formats we want to hear from you. Heres what youll do:

Laboratory Execution & Technical Support

• Design and execute bioconjugation strategies for labeling antibodies and other proteins with donor/acceptor fluorophores (NHS-ester maleimide and related chemistries); optimize reaction conditions purification and labeling efficiency from first principles
• Develop homogeneous immunoassays (TR-FRET HTRF AlphaLISA MSD and/or ELISA) for analyte detection; own the full development cycle from reagent selection and antibody pairing through format optimization and matrix validation
• Lead independent antibody screening campaigns to identify optimal capture/detection pairs; apply structured DOE approaches to optimize reagent concentrations buffer formulations and assay window
• Conduct routine assay validation experiments including precision accuracy linearity and range determination
• Prepare biological samples reagents and buffers according to SOPs
• Operate and maintain laboratory equipment including plate readers liquid handlers and analytical instruments
• Independently diagnose and resolve assay performance failures; apply root-cause analysis to reagent buffer and instrument variables and propose data-driven corrective actions
• Support antibody screening and characterization activities
• Assist with benchmarking studies comparing assay performance to competitor products

Data Management & Documentation

• Maintain detailed accurate and organized laboratory notebooks documenting all experimental procedures and observations
• Analyze experimental data using GraphPad Prism Excel or similar software
• Generate clear data summaries graphs and tables for internal reports and presentations
• Contribute to technical reports and validation documents
• Assist in drafting sections of SOPs and user manual protocols
• Ensure all documentation meets company quality standards and regulatory requirements

Collaboration & Learning

• Work collaboratively with Senior Scientist and other team members to support project timelines
• Participate in team meetings and provide updates on experimental progress
• Communicate experimental results and technical challenges effectively to the supervisor
• Actively seek learning opportunities to develop technical skills in bioconjugation and immunoassay development
• Support cross-functional activities with Manufacturing Quality and Marketing teams as needed
• Participate in training programs to enhance scientific and professional development

Compliance & Safety

• Adhere to all site employee health and safety (EHS) and IT security requirements
• Demonstrate and promote the company vision and values
• Maintain regular attendance and punctuality
• Conduct all activities in a safe and efficient manner
• Perform other duties as assigned
• Meet project deadlines and adjust work hours as needed to support team objectives

Qualifications :

Here is who and what we are are looking for in the ideal candidate:

Education/Experience (BMQ)

• BS/MS in chemistry biochemistry biology or related discipline with 37 years of hands-on industrial experience developing immunoassays from scratch (ELISA MSD TR-FRET/HTRF AlphaLISA or equivalent); experience must include reagent selection antibody screening and quantitative assay optimization not solely protocol execution
• Demonstrated experience independently developing and validating immunoassays including reagent pair selection signal-to-noise optimization and characterization studies with a verifiable track record of assays taken from concept to validated format
• Solid understanding of antibody-antigen binding kinetics epitope considerations for sandwich vs. competitive immunoassay design and the impact of protein biochemistry on assay performance
• Familiarity with aseptic technique and cell culture is a plus

Ability and/or Skills (BMQ)

• Strong laboratory skills with attention to detail and accuracy
• Basic proficiency in data analysis using Excel; familiarity with GraphPad Prism or similar software is a plus
• Good organizational and time management skills with the ability to balance multiple tasks
• Ability to design experiments from first principles generate and test hypotheses and translate results into actionable next steps not limited to following pre-written protocols
• Strong work ethic with demonstrated reliability and accountability
• Eagerness to learn new techniques and acquire new scientific knowledge
• Good verbal and written communication skills
• Team player with positive attitude and willingness to collaborate
• Ability to work independently on assigned tasks while knowing when to seek guidance
• Comfortable working in a fast-paced laboratory environment with defined deadlines

Additional Preferences

• Experience developing assays in two or more immunoassay platforms (e.g. ELISA MSD/ECL TR-FRET/HTRF AlphaLISA Luminex); cross-platform familiarity is a strong differentiator
• Hands-on bioconjugation experience beyond kit use: NHS-ester maleimide aldehyde or click-chemistry conjugation of small molecules haptens or fluorophores to antibodies or proteins including optimization of degree of labeling (DOL) and purification
• Hands-on experience with multi-channel pipettes automated liquid handlers and plate readers
• Familiarity with time-resolved fluorescence or FRET-based detection principles (TR-FRET/HTRF LANCE or AlphaLISA); experience with plate reader instrumentation for fluorescence or luminescence readouts (e.g. PHERAstar EnVision or equivalent)
• Academic or industrial research experience in drug discovery diagnostics or related areas
• Experience maintaining detailed laboratory notebooks and documentation
• Applied experience with Design of Experiments (DOE) for reagent concentration and buffer optimization not merely theoretical familiarity
• Experience presenting research findings in laboratory meetings or scientific conferences
• Demonstrated problem-solving skills and scientific curiosity
• Proficiency with Microsoft Office Suite (Word Excel PowerPoint)

Additional Information :

Salary Range: $95000 - $125000/yr. 

• Excellent full time benefits including comprehensive medical coverage dental and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.

Remote Work :

No

Employment Type :

Full-time