Research Associate, Automation & Screening (6 Month Contract)
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Job Location:
Boston, NH - USA
Monthly Salary:
Not Disclosed
Posted on:
Yesterday
Vacancies:
1 Vacancy
Job Summary
Overview
Monte Rosa Therapeutics is seeking a motivated Contract Research Associate for 6 months to contribute to our mission of eliminating disease-causing proteins through targeted protein degradation an innovative approach that enables us to target proteins once considered undruggable. The ideal candidate will have strong expertise in Cell and Molecular Biology utilizing CRISPR techniques in a drug discovery setting. You will join a fast-paced and innovative team environment that values teamwork collaboration and scientific rigor.
Responsibilities
- Engineer mammalian cell lines by CRISPR technology (KI and KO) and lentiviral transduction.
- Culture a variety of cell lines and primary cells testing compound-induced target degradation by Western Blot JESS and plate-based assays
- Assess pathway modulation by using pharmacological and genetic target perturbation strategies.
- Keep meticulous records of experiments on ELN.
Qualifications
B.S. or M.S. in Biotechnology Molecular Biology Genetics or related field with 1-3 years of industry experience.
Extensive experience with cell culture techniques including transient transfection lentiviral transduction CRISPR NanoBiT and NanoBRET. Experience handling primary cells desired.
Experience with molecular biology techniques (ELISAs Western Blot PCR vector design sequencing analysis).
Immunology background is a plus.
Previous experience with lab automation and high throughput data management analysis and visualization (e.g. Spotfire CDD Vault Genedata) is a plus.
Excellent oral and written communication skills.
Required Experience:
IC
Key Skills
About Company
Pioneering Therapies for Cancer and Beyond – Our drug discovery platform is tailored to promote specific protein ubiquitination and subsequent proteasomal degradation of disease-causing, undruggable proteins, in essence leading to pharmacological protein knockout with high efficiency ... View more
