| Classification Title: | PostDoctoral Associate |
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| Classification Minimum Requirements: | The appointee shall have received the doctorate in a field appropriate to the assigned duties and responsibilities. |
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| Job Description: | A unique opportunity to lead a cuttingedge translational program that integrates multiomics pharmacogenomics and highthroughput drug screening to uncover novel therapeutic strategies for acute and chronic leukemias. The successful candidate will craft independent experiments analyze patientderived leukemia phenotypes and author highimpact manuscripts while collaborating closely with clinical computational and pharmacology specialists. This is 12month appointment with potential for renewal. - Design & Execution of Experiments Develop hypothesisdriven protocols that combine genomic transcriptomic proteomic and metabolomic profiling of patient bonemarrow and peripheralblood samples with drugresponse assays and phenotypic screens (e.g. viability apoptosis stemcell niche interaction).
- Multiomics Data Generation & Analysis Lead nextgeneration sequencing massspectrometry or singlecell sequencing projects; perform rigorous bioinformatic pipelines integrate datasets and extract actionable biomarkers.
- Pharmacogenomic & DrugScreening Work Conduct highthroughput drug libraries (smallmolecule antibody targeted agents) on primary leukemia cells and engineered cell lines; interpret doseresponse resistance and synergy data; correlate findings with omic signatures.
- Interdisciplinary Collaboration Serve as the primary liaison between clinic (hematology/oncology) bioinformatics teams and pharmaceutical partners; coordinate data sharing coauthor manuscripts and present results at multidisciplinary meetings.
- Manuscript Development & Publication Draft revise and submit manuscripts to top-tier journals; oversee figures tables supplementary materials and data availability statements; manage opendata deposition (e.g. dbGaP GEO).
- Mentorship & Training Mentor undergraduate interns and research assistants; deliver training on omics workflows bioinformatics tools and drugscreening technologies.
- Regulatory & Safety Compliance Ensure all patientderived work complies with institutional IRB HIPAA and biosafety regulations; maintain detailed SOPs and instrument logs.
|
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| Expected Salary: | Commensurate with education and experience Employment Benefits include: Health Insurance: UF participates in state- and university-sponsored benefits programs for individuals families and domestic partners and offers voluntary insurance that includes vision dental long-term disability and more. Retirement Options: You may be eligible to participate in the FICA Alternative Plan and other deferred retirement plans. Leave: Full-time post-doctoral associates earn paid leave bi-weekly. To learn more visit: Qualifications: - Ph.D. in Biology Bioinformatics Genetics or related field with a strong quantitative background.
- Published record of independent research in leukemia oncology or systems biology (3 peerreviewed papers).
- Handson experience with at least two omics modalities (e.g. RNAseq ATACseq MSbased proteomics).
- Expertise in pharmacogenomics: variant annotation pathway modeling or druggenotype interaction analyses.
- Proven skill in highthroughput screens (2000 compounds per experiment) and phenotypic data analysis.
- Familiarity with bioinformatics software (e.g. R Python GSEA PRISM CellProfiler) and cloudbased data platforms.
- Strong written and oral communication skills; ability to lead interdisciplinary projects.
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| Preferred: | - Innovative thinker with a track record of designing novel experimental approaches.
- Comfortable navigating complex patientderived sample logistics and biobanking workflows.
- Eager to engage with industry collaborators and contribute to translational pipelines.
- Ability to train others quickly and maintain a collaborative lab environment.
|
|---|
| Special Instructions to Applicants: | To be considered you must upload your CV statement of research interests and a list of three professional references. As a part of our review for research and research support positions we look for a full CV which includes all professional appointments/engagements all post-secondary education and all publications from post-secondary education and all respective dates. Please be sure to not use acronyms in your CV. This CV should include names of entities associated with any projects. Application must be submitted by 11:55 p.m. (ET) of the posting end date. |
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| Health Assessment Required: | Yes |
|---|
Classification Title:PostDoctoral AssociateClassification Minimum Requirements:The appointee shall have received the doctorate in a field appropriate to the assigned duties and responsibilities.Job Description:A unique opportunity to lead a cuttingedge translational program that integrates multiomic...
| Classification Title: | PostDoctoral Associate |
|---|
| Classification Minimum Requirements: | The appointee shall have received the doctorate in a field appropriate to the assigned duties and responsibilities. |
|---|
| Job Description: | A unique opportunity to lead a cuttingedge translational program that integrates multiomics pharmacogenomics and highthroughput drug screening to uncover novel therapeutic strategies for acute and chronic leukemias. The successful candidate will craft independent experiments analyze patientderived leukemia phenotypes and author highimpact manuscripts while collaborating closely with clinical computational and pharmacology specialists. This is 12month appointment with potential for renewal. - Design & Execution of Experiments Develop hypothesisdriven protocols that combine genomic transcriptomic proteomic and metabolomic profiling of patient bonemarrow and peripheralblood samples with drugresponse assays and phenotypic screens (e.g. viability apoptosis stemcell niche interaction).
- Multiomics Data Generation & Analysis Lead nextgeneration sequencing massspectrometry or singlecell sequencing projects; perform rigorous bioinformatic pipelines integrate datasets and extract actionable biomarkers.
- Pharmacogenomic & DrugScreening Work Conduct highthroughput drug libraries (smallmolecule antibody targeted agents) on primary leukemia cells and engineered cell lines; interpret doseresponse resistance and synergy data; correlate findings with omic signatures.
- Interdisciplinary Collaboration Serve as the primary liaison between clinic (hematology/oncology) bioinformatics teams and pharmaceutical partners; coordinate data sharing coauthor manuscripts and present results at multidisciplinary meetings.
- Manuscript Development & Publication Draft revise and submit manuscripts to top-tier journals; oversee figures tables supplementary materials and data availability statements; manage opendata deposition (e.g. dbGaP GEO).
- Mentorship & Training Mentor undergraduate interns and research assistants; deliver training on omics workflows bioinformatics tools and drugscreening technologies.
- Regulatory & Safety Compliance Ensure all patientderived work complies with institutional IRB HIPAA and biosafety regulations; maintain detailed SOPs and instrument logs.
|
|---|
| Expected Salary: | Commensurate with education and experience Employment Benefits include: Health Insurance: UF participates in state- and university-sponsored benefits programs for individuals families and domestic partners and offers voluntary insurance that includes vision dental long-term disability and more. Retirement Options: You may be eligible to participate in the FICA Alternative Plan and other deferred retirement plans. Leave: Full-time post-doctoral associates earn paid leave bi-weekly. To learn more visit: Qualifications: - Ph.D. in Biology Bioinformatics Genetics or related field with a strong quantitative background.
- Published record of independent research in leukemia oncology or systems biology (3 peerreviewed papers).
- Handson experience with at least two omics modalities (e.g. RNAseq ATACseq MSbased proteomics).
- Expertise in pharmacogenomics: variant annotation pathway modeling or druggenotype interaction analyses.
- Proven skill in highthroughput screens (2000 compounds per experiment) and phenotypic data analysis.
- Familiarity with bioinformatics software (e.g. R Python GSEA PRISM CellProfiler) and cloudbased data platforms.
- Strong written and oral communication skills; ability to lead interdisciplinary projects.
| |
|---|
| Preferred: | - Innovative thinker with a track record of designing novel experimental approaches.
- Comfortable navigating complex patientderived sample logistics and biobanking workflows.
- Eager to engage with industry collaborators and contribute to translational pipelines.
- Ability to train others quickly and maintain a collaborative lab environment.
|
|---|
| Special Instructions to Applicants: | To be considered you must upload your CV statement of research interests and a list of three professional references. As a part of our review for research and research support positions we look for a full CV which includes all professional appointments/engagements all post-secondary education and all publications from post-secondary education and all respective dates. Please be sure to not use acronyms in your CV. This CV should include names of entities associated with any projects. Application must be submitted by 11:55 p.m. (ET) of the posting end date. |
|---|
| Health Assessment Required: | Yes |
|---|
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Job Location:
Monthly Salary:
Not Disclosed
Posted on:
7 days ago
Vacancies:
1 Vacancy
