Scientist II
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Job Location:
South San Francisco, CA - USA
Monthly Salary:
Not Disclosed
Posted on:
5 hours ago
Vacancies:
1 Vacancy
Job Summary
Scientist II (Contract) - Bioconjugation and Delivery
Working Model: Fully on-site
Working Model: 8 hours per day; Monday through Friday
Description
The Bioconjugation and Delivery group in the Protein Sciences organization at Genentech is responsible for the design and generation of new therapeutic modalities that combine the engineering and analytical principles of multiple scientific disciplines. We are excited to be at the forefront of therapeutic design by generating molecules with unique mechanisms of action. We are seeking a talented early-in-career Scientist to join our team to advance our mission by learning and applying advanced bioconjugation techniques with precise analytical characterization. This position offers hands-on experience in drug development including protein bioconjugation.
This position is located in South San Francisco and is an on-site laboratory research position.
Key Responsibilities
Bioconjugation of proteins utilizing chemical and/or enzymatic conjugation methods including reaction design and optimization.
Development optimization and implementation of purification protocols of bioconjugates using common protein purification techniques.
Analytical characterization of reaction mixtures and purified conjugates employing chromatographic techniques (e.g. SEC HIC IEX) SDS-PAGE colorimetric assays as well as 1D and 2D mass spectrometry.
Data reporting interpretation of results and data presentation to internal teams.
Sample management of completed conjugates and related starting materials using internal inventory systems.
Collaboration with scientists from multiple functional and therapeutic areas at Genentech to advance molecules through the drug discovery pipeline.
Required Education:
Must have attained a Bachelors Degree or higher.
Required majors:
Chemistry biochemistry chemical biology biophysics biology biomedical engineering or related fields.
Required skills:
Basic understanding of protein purification and analytical techniques.
Previous experience with FPLC HPLC or LCMS.
Excellent communication collaboration and interpersonal skills.
Other Preferred Qualifications:
Previous experience with oligonucleotides and/or antibody oligonucleotide generation
Duration: 12 months
Location: South SFO CA
Interview Format: Two Rounds (1. Hiring Manager - Virtual; 2. Panel - on-site)Working Model: Fully on-site
Working Model: 8 hours per day; Monday through Friday
Description
The Bioconjugation and Delivery group in the Protein Sciences organization at Genentech is responsible for the design and generation of new therapeutic modalities that combine the engineering and analytical principles of multiple scientific disciplines. We are excited to be at the forefront of therapeutic design by generating molecules with unique mechanisms of action. We are seeking a talented early-in-career Scientist to join our team to advance our mission by learning and applying advanced bioconjugation techniques with precise analytical characterization. This position offers hands-on experience in drug development including protein bioconjugation.
This position is located in South San Francisco and is an on-site laboratory research position.
Key Responsibilities
Bioconjugation of proteins utilizing chemical and/or enzymatic conjugation methods including reaction design and optimization.
Development optimization and implementation of purification protocols of bioconjugates using common protein purification techniques.
Analytical characterization of reaction mixtures and purified conjugates employing chromatographic techniques (e.g. SEC HIC IEX) SDS-PAGE colorimetric assays as well as 1D and 2D mass spectrometry.
Data reporting interpretation of results and data presentation to internal teams.
Sample management of completed conjugates and related starting materials using internal inventory systems.
Collaboration with scientists from multiple functional and therapeutic areas at Genentech to advance molecules through the drug discovery pipeline.
Required Education:
Must have attained a Bachelors Degree or higher.
Required majors:
Chemistry biochemistry chemical biology biophysics biology biomedical engineering or related fields.
Required skills:
Basic understanding of protein purification and analytical techniques.
Previous experience with FPLC HPLC or LCMS.
Excellent communication collaboration and interpersonal skills.
Other Preferred Qualifications:
Previous experience with oligonucleotides and/or antibody oligonucleotide generation
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
