Senior Scientist – Small Scale Oligonucleotide Synthesis (80-100)

Basel - Switzerland

Monthly Salary: Not Disclosed

Posted on: 13 hours ago

Vacancies: 1 Vacancy

Job Summary

Job Description Summary

Location: Basel Switzerland
Full time onsite #LI-Onsite

At Novartis we are reimagining medicine to improve and extend peoples lives. We use innovative science and technology to address some of societys most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help even more patients in need We believe the answers are found when curious courageous and collaborative people are empowered to ask new questions make bolder decisions and take smarter risks.

At Biomedical Research in Basel Switzerland we are at the core of Novartis purpose designing and making new molecules for treating patients. We are looking for a highly motivated passionate researcher with a strong scientific background in chemistry or related life science disciplines a curious mind-set and cultural agility to invent innovative medicines and advance the frontiers of drug discovery. Join us and help reimagine medicine!

Job Description

The Biomedical Research RNAi Initiative is seeking a passionate creative scientist to join our RNA synthesis team. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs.

Your responsibilities

Plan and execute small scale oligonucleotide syntheses by array-based automated synthetic technologies
Experiment in a first-class laboratory infrastructure and provide novel siRNAs to progress therapeutic siRNA projects
Together with the project team integrate experimental data to develop scientific hypotheses and prioritize novel oligonucleotide chemistries to address key project questions
Support and coach other team members by sharing your know-how and experience across your work environment
Discuss and communicate scientific results at internal meetings and research boards
Responsibility to maintain high levels of laboratory safety and infrastructure

What you will bring to the role

Masters educated with minimum 3 yrs industry Pharma Lab experience with a focus on synthetic organic chemistry. PhD graduates within 6 months of their defence may be considered. Please note that this role will comprise a significant percentage of wetlab activities and will not have team management responsibilities.
Practical knowledge in small scale oligonucleotide synthesis is required
Knowledge in conjugation to linkers modifiers payloads is considered a plus
Passion for automated oligonucleotide chemistry experimentation in the laboratory
Ability to critically interpret results build new experimental hypotheses and take calculated risks and smart decisions
Interest in disruptive technologies and science trends such as new drug modalities and automation and their application to drug discovery and development
A mindset of curiosity creativity collaboration and openness to diverse thinking with an enthusiasm to develop yourself and others
An organized working style eye for detail flexibility and commitment to high quality
Aptitude to work in a fast-paced team-oriented matrix environment. To collaborate within a highly dynamic team discuss science and contribute to siRNA discovery and development.
Excellent oral and written communication skills

*Restrictions on flexible working requirements may apply and can be discussed at interview stages as necessary

Accessibility and accommodation:
Novartis is committed to working with and providing reasonable accommodation to all individuals. If because of a medical condition or disability you need a reasonable accommodation for any part of the recruitment process or in order to receive more detailed information about the essential functions of a position please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Skills Desired

Required Experience:

Senior IC

Job Description SummaryLocation: Basel SwitzerlandFull time onsite #LI-OnsiteAt Novartis we are reimagining medicine to improve and extend peoples lives. We use innovative science and technology to address some of societys most challenging healthcare issues. We discover and develop breakthrough trea...

Job Description Summary

Job Description

Your responsibilities

Plan and execute small scale oligonucleotide syntheses by array-based automated synthetic technologies
Experiment in a first-class laboratory infrastructure and provide novel siRNAs to progress therapeutic siRNA projects
Together with the project team integrate experimental data to develop scientific hypotheses and prioritize novel oligonucleotide chemistries to address key project questions
Support and coach other team members by sharing your know-how and experience across your work environment
Discuss and communicate scientific results at internal meetings and research boards
Responsibility to maintain high levels of laboratory safety and infrastructure

What you will bring to the role

Masters educated with minimum 3 yrs industry Pharma Lab experience with a focus on synthetic organic chemistry. PhD graduates within 6 months of their defence may be considered. Please note that this role will comprise a significant percentage of wetlab activities and will not have team management responsibilities.
Practical knowledge in small scale oligonucleotide synthesis is required
Knowledge in conjugation to linkers modifiers payloads is considered a plus
Passion for automated oligonucleotide chemistry experimentation in the laboratory
Ability to critically interpret results build new experimental hypotheses and take calculated risks and smart decisions
Interest in disruptive technologies and science trends such as new drug modalities and automation and their application to drug discovery and development
A mindset of curiosity creativity collaboration and openness to diverse thinking with an enthusiasm to develop yourself and others
An organized working style eye for detail flexibility and commitment to high quality
Aptitude to work in a fast-paced team-oriented matrix environment. To collaborate within a highly dynamic team discuss science and contribute to siRNA discovery and development.
Excellent oral and written communication skills