Director, Biostatistics Rare Disease

Barcelona - Spain

Monthly Salary: Not Disclosed

Posted on: Yesterday

Vacancies: 1 Vacancy

Job Summary

Are you ready to lead statistical strategy that accelerates life-changing medicines for people with rare diseases Do you want to shape pivotal decisions with evidence that moves therapies faster and more confidently to patients This is a high-impact role where your expertise will guide complex programs steward external engagements and elevate the craft of biostatistics across a global network. You will build capability champion innovation and drive rigorous standards that unlock speed and value without compromising scientific integrity.

This is what you will do:

The Director Biostatistics has sufficient experience in the pharmaceutical industry to independently lead a biostatistics team to deliver project and/or technical level activities related to design delivery and interpretation high level internal governance committees and/or regulatory submissions. This individual is able to lead perform and communicate results of more technical analyses and able to guide and lead less experienced staff. Competent individual contributor with excellent cross-functional collaboration.

You willbe responsible for:

To lead manage and develop a group of statisticians
Lead the statistical design and strategy to product development plans preclinical studies regulatory strategy health technology assessment and/or commercial activities as appropriate for the stage of the product
Lead the statistical content and ensure quality for study designs documents delivery and interpretation and submission
Quantify the benefit risk value and uncertainty of the emerging product profile and can communicate these effectively within the team
Provide global leadership to others and direct project work delivered by internal and external staff
Partner with CROs to ensure delivery to quality and time
Represent Alexion externally which may include health authorities advisory boards conferences workshops and/or payer interactions
Maintain knowledge of statistical methodology in relevant areas and promote investigate and implement novel statistical approaches
Represent statistical strategy and decision making at internal decision-making governance including review boards therapy area leadership teams and ESPC/LSPC
Mentor/coach and support the technical education and training of biostatistics staff
Work according to agreed functional and regional Safety Health and Environment (SHE) strategy by ensuring proper management of SHE risks incidents reporting follow-up and improvements

You will need to have:

MSc/PhD in Statistics Mathematics (containing a substantial statistical component) or recognized equivalent to stats MSc
Track record of background in leading independently
Exemplary technical skills
Flexible well-organized and possess the ability to work well under pressure.
The duties of this role are generally conducted in an office environment. As is typical of an office-based role employees must be able with or without an accommodation to: use a computer; engage in communications via phone video and electronic messaging; engage in problem solving and non-linear thought analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

We wouldpreferfor you to have:

PhD in Statistics/Biostatistics is preferred.

At AstraZenecas Alexion division for Rare Diseases you will find an environment where work is more than just a jobits a mission. Our closeness to patients brings us closer to our work and each other. With a rapidly growing portfolio in a nimble biotech atmosphere supported by global resources tailored development programs are crafted to improve your skills. These programs encourage a deep understanding of our patients journeys. Here diversity is valued; inclusion is championed; innovation is celebrated; all while making a profound impact on patients lives.

Ready to make a difference Apply now!

Date Posted

27-Feb-2026

Closing Date

27-Mar-2026

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment training compensation promotion and other terms and conditions of employment based on race color religion creed or lackthereof sex sexualorientation age ancestry national origin ethnicity citizenship status marital statuspregnancy (including childbirth breastfeeding or related medical conditions) parental status (including adoption or surrogacy) military status protected veteran status disability medical condition gender identity or expression genetic information mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin aninteractive dialogue with Alexion regarding an accommodation please contact . Alexion participates in E-Verify.

Required Experience:

Director

This is what you will do:

You willbe responsible for:

To lead manage and develop a group of statisticians
Lead the statistical design and strategy to product development plans preclinical studies regulatory strategy health technology assessment and/or commercial activities as appropriate for the stage of the product
Lead the statistical content and ensure quality for study designs documents delivery and interpretation and submission
Quantify the benefit risk value and uncertainty of the emerging product profile and can communicate these effectively within the team
Provide global leadership to others and direct project work delivered by internal and external staff
Partner with CROs to ensure delivery to quality and time
Represent Alexion externally which may include health authorities advisory boards conferences workshops and/or payer interactions
Maintain knowledge of statistical methodology in relevant areas and promote investigate and implement novel statistical approaches
Represent statistical strategy and decision making at internal decision-making governance including review boards therapy area leadership teams and ESPC/LSPC
Mentor/coach and support the technical education and training of biostatistics staff
Work according to agreed functional and regional Safety Health and Environment (SHE) strategy by ensuring proper management of SHE risks incidents reporting follow-up and improvements

You will need to have:

MSc/PhD in Statistics Mathematics (containing a substantial statistical component) or recognized equivalent to stats MSc
Track record of background in leading independently
Exemplary technical skills
Flexible well-organized and possess the ability to work well under pressure.
The duties of this role are generally conducted in an office environment. As is typical of an office-based role employees must be able with or without an accommodation to: use a computer; engage in communications via phone video and electronic messaging; engage in problem solving and non-linear thought analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

We wouldpreferfor you to have: