Principal Scientist, Biologics Discovery

Spring House, PA - USA

Monthly Salary: Not Disclosed

Posted on: 3 days ago

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at .

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House Pennsylvania United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Principal Scientist Biologics Discovery in Spring House PA.

Job Description

Position Summary:

This position is dedicated to advancing the discovery and development of innovative biotherapeutics targeting unmet medical needs through immune-mediated approaches. As a key contributor you will leverage your expertise in Immunobiology and T-cell biology to support portfolio programs and drive the success of discovery initiatives.

You will be responsible for:

Leading or actively participating in project teams to progress discovery portfolio projects.
Driving technology development efforts for multispecific antibody platforms and validating readiness for portfolio inclusion.
Designing conducting and interpreting in vitro immune cell functional assays and related experimental studies.
Presenting and defending scientific findings independently within multidisciplinary teams and initiatives.
Authoring patent applications manuscripts study protocols SOPs and technical reports.
Managing and mentoring scientific staff.

Qualifications / Requirements:

Education:

Ph.D. degree in life sciences (molecular biology biochemistry immunology or a related discipline) with 4 years post-doctoral experience OR Masters Degree in life sciences with at least 6 years of experience is required.

Required:

Extensive understanding of immunology including in vitro and in vivo models relevant to immuno-oncology and autoimmune disease.

Demonstrated experience with immune cell based assays such as multi-color flow cytometry cytotoxicity and multiplex cytokine assays.
Experience developing novel complex and high-throughput immune assays for functional characterization and MOA studies.
Ability to work effectively in a matrixed environmentboth within the group and across the broader organization.
Strong dedication motivation and a collaborative approach to advancing therapeutic innovation.
Commitment to continuous learning and scientific excellence.
Excellent analytical and problem-solving skills for experimental design and data interpretation.
Exceptional communication skills with the ability to present complex data clearly and concisely is required.

Preferred:

Experience in end-to-end drug development processes is highly preferred.
Industry experience is highly preferred.

This job posting is anticipated to close on March 6 2026. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

#LI-Onsite

Required Skills:

Preferred Skills:

Analytical Reasoning Biochemistry Biotechnology Chemistry Manufacturing and Control (CMC) Clinical Research and Regulations Clinical Trial Designs Coaching Critical Thinking Drug Discovery Development Emerging Technologies Molecular Diagnostics Organizing Pharmacovigilance Presentation Design Process Improvements Productivity Planning Scientific Research

Required Experience:

Staff IC