Senior Scientist, Multiomic Therapeutics

Madrid - Spain

Monthly Salary: Not Disclosed

Posted on: Yesterday

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at .

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Data Analytics & Computational Sciences

Job Sub Function:

Data Science

Job Category:

Scientific/Technology

All Job Posting Locations:

Cornellà de Llobregat Barcelona Spain Madrid Spain

Job Description:

Johnson & Johnson Innovative Medicine is seeking aSenior Scientistto join theData Science & Digital Health (DSDH)organization based in this role you will drive innovative computational biology AI/ML model development and integrative omics strategies to accelerate discovery optimize therapeutics and inform clinical development for precision medicine.

Key Responsibilities

You will lead the development of an AI-powered siRNA design and off-target prediction framework to optimize siRNA selection and minimize off-target effects. You will provide technical leadership and define architecture strategies for the multiomics solution/product. You will design and execute advanced computational analyses manipulate multiomics datasets (genomic transcriptomic proteomic) from human and preclinical models drive algorithm selection/application develop AI/ML models and build reproducible pipelines. You will perform data visualization and partner with crossdisciplinary scientists to enable end-to-end strategy and execution.

In this role you will:

Develop optimize and deploy the design/prediction framework for siRNA candidate generation and transcriptome-wide off-target assessment including multi-omics/species data integration and AI/ML model developmentof off-target assessmentwide offtarget assessment
Engage with therapeutic discovery and preclinical safety teams to enable integration of computational predictions and experimental detection for end-to-end strategy/platform in RNA-based drug development.
Providetechnical leadershipand set project strategies technical milestones and delivery timelines. Ensure computational workflows follow best practices for data integrity reproducibility and engineering.

Communicate the approach and findings effectively through internal/external reports presentations and publications. Enhance the organizations Omics data foundation and technical capabilities.

Qualifications

Required:

Ph.D. in Bioinformatics Computational Biology Data Science Biomedical Engineering Computer Science Artificial Intelligence or a related field.
2 years postdoctoral or industry experience in large-scale omics data analysis (e.g. genomics and transcriptomics) preferably in therapeutic discovery and preclinical safety.
Strong AI/ML skill set for biological datasets including specificity/activity modeling. Experience in integrating transcriptomewide data and applying predictive algorithms/models.
Proficiencyin high-performance and cloud-based computing workflow design pipeline development and optimization.

Preferred:

Experience in therapeutic discovery and validation workflows. Familiarity with multi-species reference transcriptomes microRNA and genetic variation databases and RNA-based therapeutic prediction algorithms/models.

Familiarity with multi-omics models and integrating data across multiple platforms datasets and batches.
Experience in defining research strategies and setting project milestones to drive innovation.
Ability to convey complex technical concepts clearly to cross-functional teams.

Impact of the Role

In this role you will lead pioneering projects advancing therapeutic discovery and clinical development. You will work in a collaborative cross-functional research environment at the forefront of precision medicine with access to cutting-edge omics data and technologies. You will have the flexibility to work at our Spanish sites or remotely with global team integration.

Required Skills:

Preferred Skills:

Advanced Analytics Business Intelligence (BI) Coaching Collaborating Critical Thinking Data Analysis Database Management Data Privacy Standards Data Reporting Data Savvy Data Science Data Visualization Econometric Models Process Improvements Technical Credibility Technologically Savvy Workflow Analysis

Required Experience:

Senior IC