Senior Scientist, Multiomics Perturbation

Madrid - Spain

Monthly Salary: Not Disclosed

Posted on: Yesterday

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at .

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Data Analytics & Computational Sciences

Job Sub Function:

Data Science

Job Category:

Scientific/Technology

All Job Posting Locations:

Cornellà de Llobregat Barcelona Spain Madrid Spain

Job Description:

Johnson & Johnson Innovative Medicine is seeking aSenior Scientistto join theData Science & Digital Health (DSDH)organization based in this role you will lead the design execution and application of advanced computational models to integrate multimodal perturbation data and human omics datasets for target/pathway nomination.

Key Responsibilities

You will drive the development of predictive frameworks for disease state reversal nominate synergistic target combinations and perform in silico target deconvolution to inform portfolio decisions in immunemediated diseases.

In this role you will:

Lead the design optimization and validation of humanomics driven perturbation prediction models integrating CRISPR KO transcriptomics proteomics cytokine profiles and other cellular screening data to predict diseasereversal phenotypes in disease models.
Develop advanced computational strategies to perform target deconvolution identify target combinations and pathway perturbation that most effectively reverse pathogenic activity.
Build humanomics based phenotype scoring frameworks to quantify perturbation efficacy validated across internal datasets and public databases.
Collaborate closely with therapeutic discovery disease biology and preclinical safety leads to translate in vitro perturbation outcomes into relevant human disease biology insights and to translate computational outputs into experimental validation strategies.
Provide technical leadership set analytical roadmaps define milestones quantify success metrics and ensure reproducibility and scalability across workflows.

Qualifications

Required:

Ph.D. in Bioinformatics Computational Biology Data Science Biomedical Engineering Computer Science Artificial Intelligence or a related field.
2 years postdoctoral or industry experience in largescale multiomics data analysis (e.g. genomics transcriptomics proteomics) preferably in therapeutic discovery or translational research.
Proven expertise in AI/ML modeling for biological datasets prediction modeling phenotype scoring and multiomics integration.
Experience with systems biology/network analysis
Advanced skills in highperformance/cloud computing reproducible pipeline development and workflow optimization.
Excellent written and oral communication skills for multidisciplinary teams. Demonstrated record of impactful research (peerreviewed publications conference talks).

Preferred:

Experience in in vitro perturbation data analysis and chemicaltarget mapping.
Knowledge of public omics databases.
Background in network/pathway analysis and integrative data harmonization across platforms.
Familiarity with immunemediated disease biology especially fibroblast pathobiology.

Impact of the Role

In this role you will be at the forefront of J&Js initiatives to unlock novel therapeutic strategies by integrating proprietary perturbation datasets with cuttingedge computational modeling. Your work will directly advance therapeutic discovery and translational research. You will have the flexibility to work at our Spanish sites or remotely with global team integration.

Required Skills:

Preferred Skills:

Advanced Analytics Business Intelligence (BI) Coaching Collaborating Critical Thinking Data Analysis Database Management Data Privacy Standards Data Reporting Data Savvy Data Science Data Visualization Econometric Models Process Improvements Technical Credibility Technologically Savvy Workflow Analysis

Required Experience:

Senior IC