Director, Platform Science and Innovation

About the role

Revalia is pioneering Human Data Trials a new paradigm for accelerating translational medicine by linking donated human organs to cutting-edge research. Our platform provides biotech pharma and medtech innovators with unparalleled access to human biology at scale reducing reliance on animal models and speeding the path to patients.

This leader will shape Revalias innovation agenda in biomarker discovery mechanistic modeling hardware-integrated sensing and data extraction. They will ensure that the scientific engineering and modeling strategy aligns with Revalias product vision and long-term data platform. This role touches biomedical engineering device innovation software pharma modeling ML integration and IP creation making it one of the most cross-disciplinary leadership roles at the company.

The ideal candidate is a PhD-level scientist-engineer with deep industry experience across pharma medical devices and computational modelingsomeone who can define strategy lead teams collaborate with executives and also dive deep technically when needed.

Location

This position requires candidates be able to travel to New Haven CT on a weekly basis.

Culture Requirements

• Role model the Revalia Bios Company Values of world class collaboration cultivating deep trust relentless adaptability and to persevere with uncommon grit.
• Display high levels of personal integrity and be able to express opinions or concerns directly and without triangulation demonstrating honesty openness and a positive outlook at all times.
• Seek to promote collaboration and be curious (and not judgmental) about opposing opinions.
• Ability to adapt to changing business needs or to personal development opportunities. Able to fully embrace feedback and training to continuously improve performance and relationships.
• Display determination and perseverance to problem solve create innovate and develop.
• Demonstrate commitment to own personal growth and development. Be all-in when participating in Company activities and programs related to personal and professional development and training.
• Commitment to the growth and development of their team including participation in 360 reviews where requested.

Responsibilities

Strategic Leadership & Vision

• Define and lead Revalias overall non-invasive biomarker and physiological modeling roadmap with clear milestones tied to product and data strategy.
• Partner with CDIO Data Gen Engineering Product and Data Science leadership to align research hardware development and modeling work into a coherent innovation plan.
• Evaluate emerging technologies academic trends and clinical needs to guide Revalias long-term biomarker and modeling strategy.

Biomarker Discovery & Innovation

• Lead the invention characterization and validation of novel real-time non-invasive biomarkers derived from organ perfusion signals.
• Establish scientific frameworks for discovering highly repeatable translatable physiological indicators for organ function and health.
• Oversee experimental design and validation studies supporting productization and regulatory pathways.

Physiological Modeling & PB/PK Integration

• Architect and guide development of PB/PK and mechanistic physiological models tailored to high-frequency perfusion system data.
• Lead efforts to adapt classical PB/PK frameworks to dynamic real-time non-invasive measurements.
• Champion hybrid modeling approaches combining mechanistic and machine learning components.

High-Fidelity Data Extraction & System Integration

• Oversee the strategy for high-quality signal extraction calibration and harmonization from organ perfusion systems.
• Define technical standards for data quality acquisition protocols and feature engineering.
• Ensure tight integration between hardware data gen data engineering and modeling pipelines to maximize signal interpretability and value.

Sensor & Hardware Innovation

• Guide development of new non-invasive sensor technologies partnering with hardware engineering to define requirements and evaluate performance.
• Lead cross-functional investigations into sensor physics instrumentation and data acquisition for novel biomarker detection.
• Influence hardware architecture based on modeling and data insights.

ML Integration & Data Productization

• Collaborate with AI/ML teams to design hybrid mechanisticML modeling frameworks and ensure physiological model outputs are ML-ready.
• Define scientific and technical standards for integrating physiological models into RIO products.
• Set evaluation criteria truth definitions and data requirements for ML pipeline development.

IP Scientific Influence and External Strategy

• Drive creation of patentable technologies spanning sensors biomarkers modeling and signal extraction.
• Shape Revalias scientific presence through white papers publications and SAB engagement.
• Build and maintain relationships with academic collaborators industry partners and key scientific advisors.

Qualifications

• PhD in Biomedical Engineering Electrical Engineering Mechanical Engineering Chemical Engineering Bioengineering Applied Physics or related field.
• 10 years of experience across pharma medical devices diagnostics physiological modeling or computational biology.
• Demonstrated leadership in:
• • biomarker or sensor innovation
  • mechanistic physiological modeling (PB/PK strongly preferred)
  • developing data-driven digital technologies or devices
  • multidisciplinary team environments
• Strong technical background in non-invasive sensing (imaging spectroscopy digital health) signal processing instrumentation or device R&D.
• Experience building validating and interpreting models from experimental biological systems.
• Hands-on coding experience in Python MATLAB R or similar scientific computing ecosystems.
• Experience integrating models or algorithms into software systems or digital products.
• Proven track record of patent development published research or developing novel methodologies.
• Experience collaborating with software and ML teams; ability to define requirements for hybrid modeling systems. Proven track record of creating analytical solutions at scale.
• Strong communication scientific leadership and cross-functional collaboration skills.

Preferred:

• Experience in early-stage startups or leading innovation programs.
• Experience with real-time or streaming physiological data systems.
• Familiarity with regulatory considerations for devices diagnostics or computational models.
• Familiarity with AI/ML workflows MLOps or ML feature engineering.
• Demonstrated success transitioning research into productized capabilities or clinical/engineering decision tools.

Compensation Benefits and Diversity Commitment

Our compensation structure includes a base and semi-annual bonus. The range for this role is $160000 - $200000 annually. Revalia Bio operates a growth culture focused on High Performance Teams and individual personal development. Along with monthly coaching we provide extensive opportunities for professional development training and mentoring.

Revalia Bio provides comprehensive benefits including Health Dental Vision Retirement Disability and a wellness program available on day one of employment. Full-time employees are eligible for up to 5 paid sick days and 23 PTO days per calendar year excluding national holidays.

Revalia Bio acknowledges and celebrates the diversity of our workforce is dedicated to creating an equitable workplace is committed to fostering an inclusive environment and aims to create a workplace culture where every individual feels a sense of belonging. We are an equal opportunity employer and do not discriminate on the basis of race religion color national origin sex sexual orientation gender gender identity or expression age disability or genetic makeup. For individuals with disabilities who would like to request an accommodation please email

Required Experience:

Director