Bioinformatics Analyst II Seibold Moore Lab

The Seibold and Moore Laboratories are seeking a passionate and highly motivated Bioinformatics Analyst II to join our cutting-edge NIH-funded research team. Our laboratories bring together an interdisciplinary group of experts in cell biology skin and molecular biology alongside experts in computational biology bioinformatics and statistical genetics. Our research focuses on unraveling the complex pathobiological mechanisms underlying atopic dermatitis food allergy asthma and other allergic diseases. The goal of our work is to identify and characterize pathobiological subtypes (i.e. endotypes) of allergic disease and to determine the genetic environmental and immunological factors that drive disease development progression and treatment response.

The successful candidate will lead bioinformatics and biostatistical analyses to investigate how different types of skin pathobiology (i.e. endotypes) present in early life underlie the development of atopic dermatitis and how this early life skin dysfunction subsequently leads to the development of other allergic diseases including food allergy allergic rhinitis and asthma. Specifically the successful candidate will::

• Implement pipelines and workflows for RNA-sequencing whole genome sequencing eQTL mapping and transcriptome wide association studies
• Conduct statistical analysis and data visualization for longitudinal gene expression data
• Interpret and explain results
• Write manuscripts for publication
• Collaborate with a diverse research team

Required Qualifications:

• Bachelors degree in bioinformatics biostatistics computer science or related field
• Experience with bioinformatics tools and high-throughput genetic/genomic data analysis
• Proficiency in UNIX/LINUX and high-performance computing environments
• Strong programming skills (e.g. R Python Perl Java C)
• Familiarity with statistical methods and data analysis
• Excellent communication skills and the ability to manage multiple projects

Preferred Skills:

• Masters or Ph.D. in a relevant field
• Experience with RNA-seq single-cell RNA-seq and eQTL mapping
• Background in allergic diseases especially atopic dermatitis and food allergy

Position Summary
Provides advanced bioinformatics support to scientists.

Essential Duties

1. Collaborates with and supports scientists in the area of bioinformatics analysis.
2. Assists with the design and development of major bioinformatics-related programming projects.
3. Writes custom scripts to access databases and analyze data.
4. Writes custom web tools for scientists.
5. Assists with the preparation and teaching of courses and/or demonstrations on the use of bioinformatics tools.
6. Interprets complex biological information. Performs tasks to reduce and consolidate output from software. Prepares data for utilization by other scientists.
7. Develops and uses gene/protein functional annotation tools and programs.
8. May develop and maintain searchable databases.
9. May direct and guide DNA RNA small molecule and protein sequence database searches and the computational analysis of resulting data.
10. Uses version control and other reproducible research practices.
11. Writes sections for reports and other dissemination of research methods and findings.

Competencies

1. Accountability: Accepts full responsibility for self and contribution as a team member; displays honesty and truthfulness; confronts problems quickly; displays a strong commitment to organizational success and inspires others to commit to goals; demonstrates a commitment to National Jewish Health.
2. Attention to Detail: Accomplishing tasks by considering all areas involved no matter how small; showing concern for all aspects of the job; accurately checking processes and tasks; being watchful over a period of time. Setting high standards of performance for self and others; assuming responsibility and accountability for successfully completing assignments or tasks; self-imposing standards of excellence rather than having standards imposed.
3. Collaboration/Teamwork: Cooperates with others to accomplish common goals; works with employees within and across his/her department to achieve shared goals; treats others with dignity and respect and maintains a friendly demeanor; values the contributions of others.
4. Informing and Communicating: Clearly conveying information and ideas through a variety of media to individuals or groups in a manner that engages the audience and helps them understand and retain the message.
5. Initiative: Taking prompt action to accomplish objectives; taking action to achieve goals beyond what is required; being proactive.
6. Managing Work and Time/Project Management: Effectively managing ones time and resources to ensure that work is completed efficiently. Effectively manages project(s) by appropriately focusing attention on the critical few priorities; effectively creates and executes against project timelines based on priorities resource availability and other project requirements (i.e. budget); effectively evaluates planned approaches determines feasibility and makes adjustments when needed.
7. Problem Solving: Uses issue identification data relation and comparison pattern recognition and information gathering to create analyses and make recommendations.

Minimum Qualifications

1. Education: Bachelor of Arts (BA) or Bachelor of Science (BS) required in bioinformatics biostatistics or computer science or related field required. Masters or PhD in computational field preferred.
2. Work Experience:A minimum of 3 years of applied experience required.
3. Special Training Certification or Licensure:Must be proficient in at least 2 programming languages (e.g. python C JAVA Etc.) and have a background in utility programming (Bash AWK Perl BioPerl R Matlab and other languages) in a Linux environment.

Salary Range: $58656.00 - $77572.56

Benefits
At National Jewish Health we recognize that our outstanding faculty and staff are the essence of our organization. For every aspect of health care our employees are our greatest asset. With that in mind we have designed a valuable comprehensive benefits package to meet the needs of our employees and their families.

• Comprehensive Medical Coverage:Multiple Cigna health plans for Colorado regional office and remote employees. Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA) available to pair with some plans.
• Paid Time Off:Generous PTO accruals to use for vacation and sick days and six paid holidays all compliant with Colorado state sick leave regulations.
• Dental & Vision Plans:Coverage effective the first of the month after hire.
• Retirement Savings:403(b) plan with employer contributions after two years.
• Wellness Incentives:Earn up to $200 annually for preventive health activities.
• Tuition Reimbursement:Up to $5250 annually for full-time and part-time employees.
• Child Care Assistance:Childcare Flex Spending Account (FSA) with annual employer contribution.
• Loan Forgiveness:Public Service Loan Forgiveness (PSLF) eligible employer.
• Disability & Life Insurance:Employer-paid plans and optional buy-up choices.
• Voluntary Benefits:Full suite of coverage options such as Accident Hospital Indemnity and Legal Plan
• Exclusive Discounts:Savings on local services insurance and RTD bus passes.