Research Scientist I- Cell BiologistHigh Throughput Screening
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Job Location:
Cambridge, MA - USA
Monthly Salary:
Not Disclosed
Posted on:
Yesterday
Vacancies:
1 Vacancy
Job Summary
General information
Description & Requirements
Were looking for a passionate and skilled Cell Biologist with High Throughput Screening experience to join our CDoT Collaborative Screening team. Reporting to an Associate Director youll be a key member of our multidisciplinary teams helping to drive the development and execution of predominantly cell-based high throughput screens. Your work will directly empower target validation assay development hit discovery and validation. Ideally you have experience with a variety of assay formats within a drug discovery or therapeutics context.
Key Responsibilities
Independently design and execute cell-based assays for drug discovery projects including both genetic and small molecule screening in various high throughput formats.
Culture and maintain diverse cell lines and primary cells with a high degree of precision.
Collaborate coordinate and communicate with cross-functional teams to advance therapeutic projects and ensure that research plans timelines and deliverables are met.
Analyze interpret explain and present experimental data research plans and results to both internal teams and external collaborators.
Innovate new cellular assay methods and contribute to a fast-paced dynamic research environment.
Supervise train and mentor junior members of the team.
Qualifications
Required Qualifications:
Ph.D. with 1-2 years or a Masters degree with 7-10 years experience in cell biology chemical biology or high throughput screening
Demonstrated in-depth experience in culturing deriving and maintaining various cell lines.
Proven ability to work both collaboratively within a team and independently to meet project goals; makes data-driven decisions for forward progress
Maintain detailed experimental records documentation and written protocols
Excellent communication organization and time management skills.
Must show strong ability to be flexible to adapt and effectively manage changes in a fast-paced dynamic environment and troubleshoot.
Preferred Qualifications:
Experience with the development and execution of plate-based assays such as Cell Titer-Glo viability assay immunofluorescence staining and biochemical assays as well as high-throughput screening and automation.
Experience with advanced techniques such as high-content imaging or molecular biology (e.g. qPCR western blotting ELISA).
Experience with FLIPR (Fluorescence Imaging Plate Reader) assays to measure intracellular calcium flux membrane potential and ion channel activity.
Ability to mentor junior trainees
Required Experience:
IC
Key Skills
- Laboratory Experience
- Machine Learning
- Python
- AI
- Bioinformatics
- C/C++
- R
- Biochemistry
- Research Experience
- Natural Language Processing
- Deep Learning
- Molecular Biology
About Company
Broad Institute is a multidisciplinary community of researchers on a mission to improve human health.
