Postdoctoral Fellow in Structural Biology of RNA Metabolism
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1 Vacancy
Job Summary
About us
The Kowalinski group aims to understand how gene expression is regulated through diverse RNA processing pathways. We investigate emerging concepts in eukaryotic RNA processing including mechanisms of RNA maturation editing and chemical modification in a protist model organism. Our research spans both fundamental mechanistic questions and applied biological challenges.
Your role
As a postdoctoral researcher you will contribute to the structural and biochemical characterization of previously uncharacterized parasitic RNA-processing complexes. You will integrate molecular biology biochemistry computational modelling and structural approaches to uncover mechanistic insights into eukaryotic RNA processing pathways. Your work will involve isolating complexes directly from cell culture as well as using recombinant expression systems or defined mixtures to reconstitute specific functional states. You will characterize these assemblies using cryo-electron microscopy high-resolution imaging biochemistry and biophysics to elucidate how cellular RNA-processing nanomachines function.
You have
The successful candidate is deeply interested in RNA-processing machineries and holds a PhD in Molecular Biology Biochemistry Biophysics Structural Biology or a related discipline. Strong hands-on experience in the integration of structural and molecular biology techniques including cryo-EM purification of macromolecular complexes from recombinant and endogenous sources protein biochemistry and biophysical methods is essential.
An interest in protozoan biology is expected and prior experience with the genetic manipulation of model systems will be considered a strong advantage. Familiarity with complementary methods such as computational structural biology tools mass spectrometry advanced imaging and RNA sequencing methodologies is advantageous.
Excitement for science and discovery strong experimental troubleshooting skills in-depth data analysis abilities out-of-the-box thinking a collaborative mindset excellent communication skills in English and a proven publication record are required. Knowledge of French is not necessary.
Contract length:1 year with the possibility of extension
Application:Please submit a CV with a publication list and a letter of motivation outlining your research interests fit to the lab and long-term plans.
Professional development support
The EMBL Fellows Career Service provides support and guidance to predoctoral and postdoctoral fellows across all six EMBLs sites.
Working with a dedicated Careers Advisor this invaluable service will help you to take informed decisions about your career planning both in the short and longer term. Whether your main interest is pursuing a career path in academia exploring opportunities in industry or exploring an independent venture the EMBL Fellows Career Service with provide you with a portfolio of activities and resources to help you.
To find out more please visit - EMBL-fellows-career-service
Why join us
Join a culture of innovation
We are located on the Wellcome Genome Campus alongside other prominent research and biotech organisations and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued supported and empowered to reach their professional potential.
Enjoy lots of employee benefits:
Financial incentives:Monthly family and child allowances generous stipend reviewed yearly pension scheme death benefit and unemployment insurances
Flexible working arrangements including hybrid working patterns
Private medical insurancefor you and your immediate family
Generous time off:30 days annual leave per year in addition to public holidays
Campus life:Free shuttle bus (Heidelberg) on-site library subsidised on-site cafeteria casual dress code extensive sports and social club activities (on campus and remotely)
Family benefits: Kindergarten (Heidelberg) 10 days of child sick leave paid maternity & parental leave holiday clubs on campus and monthly family and child allowances
What else you need to know
International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants.
Diversity and inclusion: At EMBL we believe that diverse teams drive innovation and scientific excellence. We encourage applications from candidates of all genders identities nationalities and/or any other diverse backgrounds.
Job location: All our fellowships are based on-site (for at least part of each week). If you are living overseas you will receive a generous relocation package to support you.
EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here
How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date.
Closing Date
01/03/2026
Key Skills
- Virology
- Bioinformatics
- Genetics
- R
- Biochemistry
- Cell Biology
- Research Experience
- Spectroscopy
- Cell Culture
- Molecular Biology
- Microscopy
- Research Laboratory Experience
About Company
With 29 member states, laboratories at six locations across Europe and thousands of scientists and engineers working together, the European Molecular Biology Laboratory is a powerhouse of biological expertise. The intergovernmental organisation, headquartered in Heidelberg, was founde ... View more
