Associate Scientist Antibody Discovery
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Job Location:
Memphis, TN - USA
Yearly Salary:
$ 65520 - 114400
Posted on:
15 hours ago
Vacancies:
1 Vacancy
Job Summary
Candidates with experience in protein engineering expression and validation of biologics are encouraged to apply.
What you will do:
- Work closely with mAb discovery platforms to support molecular biology workflows; design and execute construct generation for antibody expression.
- Perform DNA preparations to generate high-quality plasmid material for mammalian cell transfection.
- Develop and optimize high-throughput mammalian cell-based production platforms for recombinant antibodies antigens and other biologics.
- Establish scalable transient and stable expression workflows in CHO HEK293 and other mammalian expression systems.
- Purification using AKTA chromatography systems.
- High-Performance Liquid Chromatography Size Exclusion Chromatography (HPLC-SEC) analysis of purified proteins.
- Molecular assessment of early-stage development candidates (polyreactivity ELISA CE-SDS SEC-MALS DSF)
- Maintain accurate and timely ELN data
Preferred skills:
- Experience with modern AKTA chromatography systems (FPLC) for affinity capture and SEC chromatography
- Experience with high-throughput automated protein purification systems (e.g. Kingfisher)
- Experience with antibody-related bioinformatic/software packages.
- Expertise in high-throughput molecular biology approaches for construct generation
- Experience with mAb characterization techniques (FACS BLI epitope binning).
Minimum Education and/or Training:
- Bachelors degree in a relevant scientific area
Minimum Experience:
- 7 years of research experience is required
- 5 years of research experience is required with a Masters degree
- 2 years of research experience is required with a PHD
- Experience leading and supporting research experiments preferred
- Some experience leading lab and scientific project coordination maintenance and other research support activities preferred
- Experience in guiding and training other laboratory personnel preferred
- Proven performance in earlier role/comparable role
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65520 - $114400 per year for the role of Associate Scientist Antibody Discovery.Explore our exceptional benefits!
No Search Firms
St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Required Experience:
IC
Key Skills
- Laboratory Experience
- ELISA
- Immunoassays
- Transfection
- Mammalian Cell Culture
- Suspension Experience
- Biochemistry
- Assays
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
A leading children’s hospital, St. Jude treats the toughest childhood cancers and pediatric diseases. Learn about patient referrals, and donate so families never receive a bill for treatment, travel, housing or food.
