Senior Scientist, Cell Therapy Discovery
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Posted on:
15 hours ago
Vacancies:
1 Vacancy
Job Summary
Job Title: Senior Scientist Cell Therapy Discovery
Location: Cambridge UK
About the Role:
Are you ready to push the boundaries of science and transform the lives of patients living with cancer We are seeking a highly motivated independent Senior Scientist in AI/ML Computational Biology with deep expertise in machine learning applied to biology cellular therapy immunology and/or immuno-oncology to join our rapidly growing Cell Therapy team.
In this role you will contribute to the advancement of innovative Cell Therapy products by developing advanced computational models using large-scale omics datasets designing and conducting laboratory experiments and generating and interpreting scientific data in a highly collaborative environment. The role will be based in Cambridge UK.
Accountabilities:
- Design develop and deploy AI-driven machine learning and deep learning models to extract knowledge and insights from structured and unstructured data sources relevant to the development of new therapies.
- Contributes to the generation understanding and assessment of biological datasets related to functional cell biology assays and multi-omic data to generate insights relevant to drug development in Cell Therapy
- Assesses and reports data with a clear understanding of its implications within the overall context of drug discovery independently formulate conclusions and determine future experiments
- Provides technical instruction to the team and works collaboratively in a matrix environment
- Prepares and delivers presentations within the Cell Therapy Unit and across other functions
- Ensures own work and work of peers are compliant with relevant internal AstraZeneca standards and external regulations
Essential Skills/Experience:
- PhD in relevant disciplines or equivalent experience (e.g. Bioinformatics Systems Biology Computational Biology Applied Mathematics Statistics Data Science Computer Science)
- Deep understanding of model training evaluation and deployment (e.g. classical ML deep learning time-series and multimodal integration) statistical methods and reproducible workflows; hands-on experience with model families such as graph neural networks transformers and probabilistic models for high-dimensional biological data.
- Strong proficiency in Python and/or R; experience with UNIX-based systems high-performance computing (e.g. SLURM) and large-scale data management.
- Experience with single-cell and spatial transcriptomics bulk RNA-seq and integration of in vitro/in vivo datasets; ability to build robust pipelines and QC processes.
- Working knowledge of cell biology and tumor biology; interest in collaborating on in vitro studies and interpreting assays (e.g. cytotoxicity proliferation cytokine profiling multiparameter flow cytometry)
Desirable Skills/Experience:
- Hands-on experience with in vitro cytotoxicity proliferation cytokine profiling and flow cytometry.
- Experience in drug development in an industry setting.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca youll be part of a global cross-functional team that applies new knowledge and builds on diverse perspectives to keep learning. We foster a mindset of courage where everyone is empowered to innovate and work at pace. With one of the broadest Oncology pipelines in the industry youll have opportunities to work with novel drugs and make a meaningful difference for patients worldwide. Our commitment to patients and pioneering spirit are truly embedded in our values.
Ready to make an impact Apply now and join us on this exciting journey!
Date Posted
28-Jan-2026Closing Date
14-Feb-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
