Scientist Immune Reset
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Job Summary
Make your mark for patients
We are looking for aScientistwho is passionate about immunecell biology Tcell engagers and advancing nextgeneration immunotherapies to join ourImmune Resetteam based inSlough UK.
About the Role
In this role you will play a key part in progressing novel therapeutic molecules by designing developing and executing functional Tcell engager assays using primary human immune cells. You will drive mechanistic studies contribute expertise in molecular and structural biology and collaborate across departments to inform molecular engineering strategies. This is an exciting opportunity to work at the interface of immunology protein engineering and translational science.
Who Youll Work With
You will collaborate closely with immunologists structural biologists protein engineers and crossfunctional project teams. You will also present findings in internal scientific forums and contribute to highquality scientific documentation. You will help guide the structuralbiology understanding of antibodyantigen interactions and partner with colleagues across discovery and translational functions.
What Youll Do
- Design and execute functional Tcell engager assays evaluating potency specificity and mechanism.
- Perform mechanistic studies investigating immune synapse formation and Tcell activation pathways.
- Collaborate crossfunctionally to support structuralbiology interpretation and optimization strategies.
- Analyse complex immunological datasets and deliver actionable insights to project stakeholders.
- Troubleshoot technical assay challenges to drive consistency and highquality experimental outcomes.
- Present scientific results clearly during internal and crossfunctional scientific review meetings.
- Contribute to scientific reports publications and documentation supporting program advancement efforts.
- Isolate and characterize primary immune cell subsets using FACS or MACSbased approaches.
- Ensure compliance with Human Tissue Act (HTA) requirements and maintain accurate scientific records.
- Uphold health safety and SOPdriven standards across all laboratory and documentation activities.
Interested For this role were looking for:
- Demonstrated expertise in evaluating Tcell engagers using functional and phenotyping immune assays.
- Handson experience working with primary immune cells including isolation via FACS or MACS.
- Strong background in multiparameter flow cytometry immune profiling and panel design.
- Understanding of antibody engineering structurefunction principles and relevant biophysical concepts.
- Proficiency with analysis tools such as FlowJo GraphPad Prism Excel and R.
- Excellent communication teamwork and documentation practices with a strong compliance record under HTA guidelines.
Are you ready to go beyond to create value and make your mark for patients If this sounds like you then we would love to hear from you!
About us
UCB is a global biopharmaceutical company focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe inspired by patients and driven by science.
Why work with us
At UCB we dont just complete tasks we create value. We arent afraid to push forward collaborate and innovate to make our mark for patients. We have a caring supportive culture where everyone feels included respected and has equal opportunities to do their best work. We go beyond to create value for our patients and always with a human focus whether thats on our patients our employees or our planet. Working for us you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential.
At UCB weve embraced a hybrid-first approach to work bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position roles are hybrid with 40% of your time spent in the office.
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Required Experience:
IC
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
UCB – Inspired by patients. Driven by science. At UCB, we put our heart, soul and skills into making a difference for people living with severe diseases. We're here because we want to transform patients’ lives by pushing the boundaries of what is possible.To achieve our ambition, we w ... View more
