Postdoctoral Fellow Krantz Family Center for Cancer Research
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Job Location:
Boston, NH - USA
Monthly Salary:
Not Disclosed
Posted on:
4 hours ago
Vacancies:
1 Vacancy
Job Summary
Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
A postdoctoral fellowship position is available in the lab of Dr. Steve Blum at the Massachusetts General Hospital Krantz Family Center for Cancer Research and Harvard Medical School. The Blum Lab develops safer and more effective cancer immunotherapies by integrating primary human samples systems immunology and disease-relevant models to uncover mechanisms of treatment toxicity and resistance. The labs long-term goal is to inspire new therapeutic strategies and improve clinical care by maximizing anti-tumor immunity while minimizing harm. Current efforts focus on two major challenges:1. Peritoneal metastases and malignant ascites - The lab seeks to better understand the biology of this immunosuppressive microenvironment and identify novel therapeutic opportunities.
2. Immune-related adverse events (irAEs) - The lab seeks to understand the drivers of the potentially dangerous complications caused by immune checkpoint inhibitors and their relationship to anti-tumor responses to identify better models therapeutic strategies and biomarkers.
The lab is seeking highly motivated organized applicants with a PhD MD/PhD or MD and strong research training in immunology cancer biology or related fields. This position is for a researcher interested in pursuing predominantly wet-lab research. Comfort with quantitative data analysis (R/Python) is a plus and computational mentorship/collaboration is available.
The Blum Lab values teamwork scientific rigor and curiosity and it is committed to providing a supportive training environment. The lab is located in a state-of-the-art research building on the main MGH campus in Boston MA surrounded by world-class investigators across multiple disciplines. The lab is affiliated with the MGH Department of Medicine the MGH Cancer Center Harvard Medical School and the Broad Institute of MIT & Harvard providing access to cutting-edge technologies and opportunities for collaboration across Bostons vibrant biomedical community.
Key Responsibilities
- Lead and execute wet-lab experiments using patient-derived samples and relevant model systems
- Analyze and interpret results in conjunction with computational and clinical collaborators
- Prepare figures present findings drive manuscripts and craft fellowship/grant applications
- Contribute to a rigorous collaborative lab culture through teamwork and discussion
- Mentor junior trainees as appropriate
Qualifications
Highly motivated and organized individual excited to work in a collaborative fast-paced environment
PhD MD/PhD or MD with research training in biological sciences
Proficiency in basic molecular biology tissue culture and biochemical techniques
Experience with flow cytometry fluorescence microscopy organoid models immune cell engineering multi-omics workflows and/or quantitative analysis is preferred but not required.
Excellent communication organization and teamwork skills
First-authored publication(s) of scientific work
To Apply:
Interested applicants should email a cover letter CV and contact information for three references to Dr. Steve Blum (). Please include in the email subject Postdoc Application: Blum Lab.
Please do not apply through this link.
Additional Job Details (if applicable)
Remote Type
Work Location
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.
Key Skills
- Virology
- Bioinformatics
- Genetics
- R
- Biochemistry
- Cell Biology
- Research Experience
- Spectroscopy
- Cell Culture
- Molecular Biology
- Microscopy
- Research Laboratory Experience
About Company
Patients at Mass General have access to a vast network of physicians, nearly all of whom are Harvard Medical School faculty and many of whom are leaders within their fields.
