Scientist, Computational & Digital Pathology (AcelaBio)
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Job Location:
San Diego, CA - USA
Monthly Salary:
Not Disclosed
Posted on:
16 hours ago
Vacancies:
1 Vacancy
Job Summary
As a subject matter expert this role will support the execution and delivery of clinical and translational biomarker services for Sponsor and internal R&D studies. This role will function to lead and support immunostaining assay development biomarker projects and advanced image analysis including developing and applying AI-driven image analysis algorithms to quantitatively assess histopathology and biomarker data while also serving as a scientific partner to clients from study design through data interpretation and presentation.
The role will work cross-functionally with pathologists laboratory technicians scientists project operations and business development teams and will directly support pharmaceutical and biotechnology clients in planning executing and interpreting biomarker studies across preclinical and clinical programs.
Responsibilities
- What youll be doing:
- Act as a scientific interface with clients participating in client meetings protocol reviews and data review meetings
- Provide expert input on design and conduct of clinical or translational studies incorporating biomarker endpoints and omics and non-omics techniques including but not limited to immunostaining proteomics spatial biology computational and digital pathology.
- Prepare and/or support the preparation and review of project plans analysis plans and study reports abstracts manuscripts and technical reports.
- Perform and/or support the analysis and interpretation of biomarker data including providing clear scientifically rigorous data visualizations analyses and summaries.
- Partner with laboratory technicians to support immunostaining assay development optimization and validation.
- Define analytical endpoints scoring strategies and quality control metrics aligned with assay performance.
- Contribute to assay validation documentation and analytical reports as required.
- Develop validate and maintain image analysis pipelines for immunostaining (IHC) immunofluorescence (IF) in situ hybridization (ISH) and multiplex assays.
- Design and implement AI/machine learning algorithms for tissue segmentation cell characterization and biomarker quantification.
- Collaborate with pathologists through end-to-end workflows including assay development validation quantitative read-outs and interpretation.
- Ensure traceability reproducibility and documentation of analysis workflows.
- Assist with business development activities including participating in client meetings requests for proposal (RFP) responses project pricing protocol review and bid defenses as needed.
- Provide advice to sponsors seeking guidance
- Assist in the development of sales marketing and promotional materials as needed.
- Contribute to continuous improvement of computational digital pathology spatial biology and translational research capabilities.
- Assist in the development of our product/service platforms to ensure all stakeholder requirements are being considered documented and translated to the final solution.
- Participate in brainstorming meetings and functionality reviews.
Lead/Support Scientific Efforts for Computational and Digital Pathology:
Assay Development Image Analysis and Algorithm Development:
Business Development Support:
Product and Service Innovation Support:
Qualifications
- Post-graduate degree / professional designation; 7-9 years related experience plus continuous training and knowledge/skills upgrading
- Strong experience with digital pathology and image analysis
- Solid understanding of histopathology and immunostaining techniques
- Experience working in CRO laboratory biopharma and/or regulated research environment ideally supporting clinical and translational research studies
- Experience presenting data to external stakeholders or at scientific meetings
- Scientific rigor and attention to detail - able to communicate complex scientific concepts and results clearly to all stakeholders
- Strong written and oral English communication skills problem-solving and analytical thinking
- Ability to manage multiple projects in fast-paced environment with a collaborative mindset across disciplines
$150000 - $200000 a year
bonus
Compensation is dependent on the unique experience skills and education the successful candidate brings to the role. The range above represents an estimated base salary that we would expect to compensate at but we encourage applicants to speak with the member of the TA team if contacted for an initial phone screen should your expectations differ from those listed above.
We may use artificial intelligence (AI) tools to support parts of the hiring process such as reviewing applications analyzing resumes or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed please contact us.
Required Experience:
IC
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
Accelerate your GI clinical trials with Alimentiv’s site network, clinical trial services, medical imaging, and biomarker discovery
