Senior Scientist II, Biologics Purification
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Job Location:
North Chicago, IL - USA
Monthly Salary:
Not Disclosed
Posted on:
7 hours ago
Vacancies:
1 Vacancy
Job Summary
Join AbbVies Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification you will play a pivotal role in driving drug discovery collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays binding cell-based assays etc.) and in vivo studies (i.e. efficacy non-GLP NHP PK DRF etc.).
Key Responsibilities:
- Lead the purification of bispecific biologics to support critical research assays and studies
- Design and execution of robust process development strategies necessary to address production liabilities which factor into future process scalability.
- Apply advanced bioprocessing and chromatography techniques at large scale
- Utilize in silico tools DOE methodologies and predictive modeling to optimize protein separation and maximize yield/quality
- Integrate and manage analytical data using LIMS ETL tools and data extraction APIs
- Collaborate with multidisciplinary teams translating molecular insights into functional results
- Stay current with emerging scientific literature to foster innovation and continuous improvement
- Present findings clearly to diverse audiences and document results with rigor
Qualifications :
- BS MS or PhD in Bioinformatics Biophysics Chemical Engineering or related field with typically 12 years (BS) 10 years (MS) or 4 years (PhD) of experience
- Deep proficiency in large-scale bioprocessing and chromatography
- Skilled in software systems and/or programming languages: Unicorn Chromeleon Empower JMP Minitab Python SDMS platforms
- Experience with in silico tools/models and DOE to both predict and optimize protein separation behavior based upon critical process parameters.
- Experience with data extraction API ETL tools and LIMS platforms for data acquisition integration and management across multiple analytical platforms is a plus
- Strong understanding of molecular and post-translational attributes of biologics
- Exceptional analytical communication and presentation skills
- Collaborative spirit and dedication to scientific excellence
Why AbbVie Here we combine advanced science with our strong values cultivating a culture where curiosity is encouraged and meaningful contributions are recognized. Grow your career innovate boldly and make a difference in the lives of patients around the globe.
Ready to pioneer the future of biologics Apply and transform science into health at AbbVie.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuro ... View more
